Afuco™ Anti-Human NRP2 ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-703CL
Anti-NRP2 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. Anti-human neuropilin-2(NRP-2) antibodies which recognizes rrNeuropilin-2 extracellular domain can be used for obtaining a medicament intended to increase p53 expression and to induce tumour cell apoptosis in the context of an anticancer treatment.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54974/1559_D5_5_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line A549
Immunofluorescent staining of human cell line A549 shows localization to plasma membrane & nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54974/985_C1_1_blue_red_green.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39980/85830_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39980/85830_A_9_3.jpg
Normal Tissue
Figure 5 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39980/85830_A_6_6.jpg
Normal Tissue
Figure 6 Smooth muscle
Smooth muscle cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39980/85830_B_6_7.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (CAPAN-2, HUVEC TERT2, TIME, U-251 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000118257-NRP2
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Specifications
- Host Species
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95% (SDS-PAGE)
- Storage
- ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "NRP2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1810-VHH | Recombinant Anti-Human NRP2 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3397z | Mouse Anti-NRP2 Recombinant Antibody (clone 32B4) | ELISA, IF, IHC, IP, WB | Mouse IgG2b, κ |
| PABW-095 | Human Anti-NRP2 Recombinant Antibody | Block | Human IgG |
| MOB-1461CT | Recombinant Mouse anti-Rat NRP2 Monoclonal antibody (07000) | ELISA, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G054E | Anti-NRP2 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBW-095 | Human Anti-NRP2 Recombinant Antibody; Fab Fragment | Block | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBW-095 | Human Anti-NRP2 Recombinant Antibody; scFv Fragment | Block | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0152CL | Anti-Human NRP2 Recombinant Antibody (ITAC-B1) | WB, FC, FuncS, Apop | |
| TAB-0153CL | Anti-Human NRP2 Recombinant Antibody (ITAC-B2) | WB, FC, FuncS, Apop | |
| TAB-0152CL-S(P) | Anti-Human NRP2 Recombinant Antibody scFv Fragment (ITAC-B1) | WB, FC, FuncS, Apop | |
| TAB-0153CL-S(P) | Anti-Human NRP2 Recombinant Antibody scFv Fragment (ITAC-B2) | WB, FC, FuncS, Apop | |
| TAB-0152CL-F(E) | Anti-Human NRP2 Recombinant Antibody Fab Fragment (ITAC-B1) | WB, FC, FuncS, Apop |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0399MZ | Chicken Anti-NRP2 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC360 | Recombinant Anti-NRP2 Vesicular Antibody, EV Displayed (VS-0425-YC360) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4991 | Anti-Rat NRP2 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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