Anti-Human NTRK3 Recombinant Antibody scFv Fragment (2248) (CAT#: TAB-184CQ-S(P))
This antibody has the high affinity to TrkC and seems to recognize a determinant in domain 4. It appears that the epitope may be a linear epitope overlapping the boundary of domain 4 and 5.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nucleoli & nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27484/if_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to nucleoli & nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27484/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48065/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48065/if_selected.jpg
Figure 3 Cerebral cortex
(nuclear Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_B_7_5.jpg
(nuclear Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_B_7_5.jpg
Figure 4 Colon
(nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_8_3.jpg
(nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_8_3.jpg
Figure 5 Testis
(nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_6_6.jpg
(nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_6_6.jpg
Figure 6 Lymph node
(Non-nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_9_8.jpg
(Non-nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9233/30817_A_9_8.jpg
Figure 7 RNA cell line category: Cell line enriched (U-138 MG)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140538-NTRK3
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140538-NTRK3
Specifications
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- 2248
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Western Blot
- Related Disease
- Amyotrophic lateral sclerosis (ALS)
Target
- Alternative Names
- NTRK3; Neurotrophic receptor tyrosine kinase 3; TRKC; gp145(trkC); NT-3 growth factor receptor; GP145-TrkC; ETV6-NTRK3 fusion; tyrosine kinase receptor C; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein
- Gene ID
- 4916
- UniProt ID
- Q96CY4
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-181CQ | Mouse Anti-NTRK3 Recombinant Antibody (TAB-181CQ) | ELISA, IF, WB, FC | Mouse IgG1, κ |
| TAB-183CQ | Anti-Human NTRK3 Recombinant Antibody (2256) | ELISA, WB | |
| TAB-184CQ | Anti-Human NTRK3 Recombinant Antibody (2248) | Agonist, ELISA | |
| TAB-181CQ-S(P) | Mouse Anti-NTRK3 Recombinant Antibody; scFv Fragment (TAB-181CQ-S(P)) | ELISA, FC, IF, WB | Mouse scFv |
| TAB-183CQ-S(P) | Anti-Human NTRK3 Recombinant Antibody scFv Fragment (2256) | ELISA, WB |
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