Afuco™ Anti-Human OSM ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-673CL)
Anti-OSM ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The single and repeat intravenous infusions AFC-673CL is used for patients with active rheumatoid arthritis (RA).
Specific Inquiry
Figure 1 Free and Total oncostatin M in one patient following repeating dosing with GSK315234.
Choy, E. H., Bendit, M., McAleer, D., Liu, F., Feeney, M., Brett, S.,... & Toso, J. (2013). Safety, tolerability, pharmacokinetics and pharmacodynamics of an anti-oncostatin M monoclonal antibody in rheumatoid arthritis: results from phase II randomized, placebo-controlled trials.Arthritis research & therapy, 15(5), R132.
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Rheumatoid Arthritis
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "OSM"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1474z | Mouse Anti-OSM Recombinant Antibody (clone 25C2) | WB, ELISA, IHC, Neut | Mouse IgG2a |
| MOB-2223MZ | Recombinant Mouse Anti-Human OSM Antibody (clone 28002.42) | ELISA, Neut, WB | Mouse antibody |
| HPAB-0112-CN | Mouse Anti-OSM Recombinant Antibody (clone 15E10) | ELISA | Mouse IgG2a, κ |
| HPAB-0278CQ | Mouse Anti-OSM Recombinant Antibody (HPAB-0278CQ) | ELISA, IHC, FuncS, Inhib | Mouse IgG1, κ |
| HPAB-0279CQ | Human Anti-OSM Recombinant Antibody (HPAB-0279CQ) | ELISA, IHC, FuncS, Inhib | Human IgG1, κ |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1815CQ | Recombinant Rat Anti-Osm Antibody (CBL660) | Neut | IgG2b |
| NEUT-1816CQ | Recombinant Mouse Anti-OSM Antibody (17001.31) | ELISA, WB, Neut | IgG2a |
| NEUT-1817CQ | Recombinant Mouse Anti-OSM Antibody (CBL423) | WB, ELISA(Cap), Neut | IgG2a |
| NEUT-1818CQ | Recombinant Mouse Anti-OSM Antibody (CBL424) | CyTOF, ICFC, Neut | IgG2a |
| NEUT-1819CQ | Recombinant Mouse Anti-OSM Antibody (CBL150) | Neut, WB | IgG2 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2557 | Hi-Affi™ Recombinant Rabbit Anti-OSM Monoclonal Antibody (DS2557AB) | WB | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0112-CN-S(P) | Mouse Anti-OSM Recombinant Antibody (clone 15E10); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0113-CN-S(P) | Mouse Anti-OSM Recombinant Antibody (clone 10D3); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0114-CN-S(P) | Human Anti-OSM Recombinant Antibody (clone B3L2); scFv Fragment | ELISA | Human scFv |
| HPAB-0278CQ-S(P) | Mouse Anti-OSM Recombinant Antibody; scFv Fragment (HPAB-0278CQ-S(P)) | ELISA, IHC, FuncS, Inhib | Mouse scFv |
| HPAB-0279CQ-S(P) | Human Anti-OSM Recombinant Antibody; scFv Fragment (HPAB-0279CQ-S(P)) | ELISA, IHC, FuncS, Inhib | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0112-CN-F(E) | Mouse Anti-OSM Recombinant Antibody (clone 15E10); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0113-CN-F(E) | Mouse Anti-OSM Recombinant Antibody (clone 10D3); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0114-CN-F(E) | Human Anti-OSM Recombinant Antibody (clone B3L2); Fab Fragment | ELISA | Human Fab |
| HPAB-0278CQ-F(E) | Mouse Anti-OSM Recombinant Antibody; Fab Fragment (HPAB-0278CQ-F(E)) | ELISA, IHC, FuncS, Inhib | Mouse Fab |
| HPAB-0279CQ-F(E) | Human Anti-OSM Recombinant Antibody; Fab Fragment (HPAB-0279CQ-F(E)) | ELISA, IHC, FuncS, Inhib | Human Fab |
Customer Reviews and Q&As
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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