Anti-Human PTN Recombinant Antibody scFv Fragment (3B10)
CAT#: TAB-0333CL-S(P)
The antibody is an anti-PTN antibody specifically binds to pleiotrophin which is highly expressed during development but with very specific and limited expression in normal adult tissue. By neutralizing one biological activity of PTN and inhibit cancer cell growth and angiogenesis, the PTN-specific antibody can be used in the treatment of cancers such as pancreatic cancer, glioblastoma, choriocarcinoma and breast cancer.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line AF22
Immunofluorescent staining of human cell line AF22 shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/73913/1783_H10_4_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17685/164389_B_8_5.jpg
Normal Tissue
Figure 3 Testis
Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17685/164396_A_6_6.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enriched (AF22)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105894-PTN/subcellular
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Specifications
- Host Species
- Mouse
- Specificity
- Human
- Clone
- 3B10
- Related Disease
- Pancreatic cancer, glioblastoma, choriocarcinoma, breast cancer
Target
- Alternative Names
- PTN; pleiotrophin; HARP; HBNF; HBGF8; NEGF1; HBBM; OSF-1; HB-GAM; HBGF-8; HBNF-1; osteoblast-specific factor 1; heparin-binding brain mitogen; heparin binding growth factor 8; heparin-binding growth factor 8; heparin affin regulatory protein; neurite growth-promoting factor 1; heparin-binding growth-associated molecule; heparin-binding neurite outgrowth-promoting factor 1; pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)
- Gene ID
- 5764
- UniProt ID
- A0A024R778
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 3B10"
- CAT
- Product Name
See other products for "PTN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2000z | Mouse Anti-PTN Recombinant Antibody (clone 39C3) | WB, FC, IF, IHC, IP | Mouse IgG1, κ |
| MOB-1271CT | Recombinant Mouse anti-Human PTN Monoclonal antibody (EML653) | IHC-P, WB | |
| VS3-FY1223 | Recombinant Rabbit Anti-PTN Antibody (clone R01-2J3) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0333CL | Anti-Human PTN Recombinant Antibody (3B10) | IHC, IF, Block, ELISA | |
| TAB-0333CL-F(E) | Anti-Human PTN Recombinant Antibody Fab Fragment (3B10) | FuncS, Inhib | |
| TAB-290CT | Anti-Human PTN Recombinant Antibody (4B2) | WB, ELISA, IHC, Neut | |
| TAB-291CT | Anti-Human PTN Recombinant Antibody (3-4A) | WB, ELISA, IHC, Neut | |
| TAB-290CT-F(E) | Anti-Human PTN Recombinant Antibody Fab Fragment (4B2) | WB, ELISA, IHC, Neut |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2926 | Hi-Affi™ Recombinant Rabbit Anti-PTN Monoclonal Antibody (DS2926AB) | WB, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5853 | Anti-PTN Immunohistochemistry Kit | IHC | |
| VS-0525-XY5854 | Anti-Rat PTN Immunohistochemistry Kit | IHC | |
| VS-0525-XY5855 | Anti-Mouse PTN Immunohistochemistry Kit | IHC |
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