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Anti-SELL/CD62L Recombinant Antibody (Aselizumab) (CAT#: TAB-720)

Recombinant humanized (from mouse) antibody expressed in CHO binding to human SELL/CD62L. Aselizumab is an immunosuppressive drug which has been investigated for the use in severely injured patients.


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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line REH
Figure 1 IF staining of human cell line REH
(Immunofluorescent staining of human cell line REH shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51972/1676_B10_3_selected.jpg
Figure 2 IF staining of human cell line MCF7
Figure 2 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51972/1704_H2_7_cr57d82833dfda8_blue_red_green.jpg
Figure 3 IF staining of human cell line U-2 OS
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51972/1674_B10_31_blue_red_green.jpg
Normal Tissue
Figure 4 Appendix
Figure 4 Appendix
(Lymphoid tissue
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2144/5974_A_3_2.jpg
Figure 5 Lymph node
Figure 5 Lymph node
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2144/5974_A_8_8.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (Daudi, JURKAT, MOLT-4, U-266/70, U-698, U-937)
Figure 6 RNA cell line category: Cell line enhanced (Daudi, JURKAT, MOLT-4, U-266/70, U-698, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188404-SELL

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Mouse
  • Derivation
  • Humanized (from mouse)
  • Type
  • IgG4
  • Species Reactivity
  • Human
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, WB and most other immunological methods.
  • CAS
  • 395639-53-9
  • Generic Name
  • aselizumab
  • Related Disease
  • Unknown

Product Property

  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • aselizumab;395639-53-9;HuDreg-55;HuEP5C7;SMART Anti-L Selectin;SELL;selectin L;LNHR, LYAM1, lymphocyte adhesion molecule 1;L-selectin;CD62L;hLHRc;LAM 1;LAM1;Leu 8;LSEL;Lyam 1;PLNHR;gp90-MEL;pln homing receptor;lymph node homing receptor;lymphocyte adhesio

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Aselizumab"

Afuco™ Anti-SELL ADCC Recombinant Antibody (Aselizumab), ADCC Enhanced
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized (from mouse) antibody expressed in CHO binding to human SELL/CD62L. Aselizumab is an immunosuppressive drug which has been investigated for the use in severely injured patients.

See other products for "SELL"

Single-domain Antibody

CAT Product Name Application Type
NAB-2242-VHH Recombinant Anti-Human SELL VHH Single Domain Antibody Neut, ChiP, IP, FUNC Llama VHH

scFv Fragment Antibody

CAT Product Name Application Type
DrMAB-1140 Recombinant Human Anti-Human SELL Antibody scFv Fragment, clone MC39A10 ELISA, WB, ICH, IP scFv
DrMAB-1143 Recombinant Human Anti-Human SELL Antibody scFv Fragment, clone MC39A10 [HRP] ELISA, WB, ICH, IP scFv
FAMAB-0208-YC-S(P) Mouse Anti-SELL Recombinant Antibody (clone DREG-55); scFv Fragment FC, FuncS Mouse scFv
FAMAB-0209-YC-S(P) Mouse Anti-SELL Recombinant Antibody (clone DREG-200); scFv Fragment FC, FuncS Mouse scFv
FAMAB-0210-YC-S(P) Human Anti-SELL Recombinant Antibody (clone HuDREG-55); scFv Fragment FC, FuncS Humanized scFv

Humanized Antibody

CAT Product Name Application Type
TAB-0710CL Human Anti-SELL Recombinant Antibody (TAB-0710CL) ELISA Humanized antibody
TAB-0710CL-S(P) Human Anti-SELL Recombinant Antibody; scFv Fragment (TAB-0710CL-S(P)) ELISA Humanized scFv
TAB-0710CL-F(E) Human Anti-SELL Recombinant Antibody; Fab Fragment (TAB-0710CL-F(E)) ELISA Humanized Fab

Blocking Antibody

CAT Product Name Application Type
NEUT-1931CQ Recombinant Mouse Anti-SELL Antibody (DREG-56) FC, WB, BL IgG1, κ
NEUT-1932CQ Recombinant Rat Anti-SELL Antibody (MEL-14) ICC, IHC-Fr, IHC-P, IP, BL, FC IgG2a

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4409 Hi-Affi™ Recombinant Rabbit Anti-SELL Monoclonal Antibody (SI501DS) FC IgG
MOR-4410 Hi-Affi™ Recombinant Rabbit Anti-SELL Monoclonal Antibody (SI502DS) FC IgG

Recombinant Antibody

CAT Product Name Application Type
HPAB-0104-LS Human Anti-SELL Recombinant Antibody (HPAB-0104-LS) ELISA Human IgG2
VS3-QX1003 Mouse Anti-SELL Recombinant Antibody (clone 9D10D1) WB, IHC, ICC, FC, ELISA Mouse IgG1
VS3-XY1399 Mouse Anti-SELL Recombinant Antibody, FITC (clone 4ADREG56) FC, IHC, IP, WB Mouse IgG1
VS3-XY1400 Mouse Anti-SELL Recombinant Antibody, PE (clone 4ADREG56) FC, IHC, IP, WB Mouse IgG1
VS3-XY1401 Mouse Anti-SELL Recombinant Antibody (clone 4ADREG56) FC, IHC, IP, WB Mouse IgG1

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0104-LS-F(E) Human Anti-SELL Recombinant Antibody; Fab Fragment (HPAB-0104-LS-F(E)) ELISA Human Fab
FAMAB-0208-YC-F(E) Mouse Anti-SELL Recombinant Antibody (clone DREG-55); Fab Fragment FC, FuncS Mouse Fab
FAMAB-0209-YC-F(E) Mouse Anti-SELL Recombinant Antibody (clone DREG-200); Fab Fragment FC, FuncS Mouse Fab
FAMAB-0210-YC-F(E) Human Anti-SELL Recombinant Antibody (clone HuDREG-55); Fab Fragment FC, FuncS Humanized Fab
FAMAB-0211-YC-F(E) Human Anti-SELL Recombinant Antibody (clone HuDREG-200); Fab Fragment FC, FuncS Humanized Fab

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-720 Afuco™ Anti-SELL ADCC Recombinant Antibody (Aselizumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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