Afuco™ Anti-Human SHH ADCC Recombinant Antibody (MEDI-5304), ADCC Enhanced
CAT#: AFC-544CL
Anti-SHH ADCC Enhanced Antibody (MEDI-5304) is an ADCC enhanced antibody produced by our Afuco™ platform. MEDI-5304 is the first fully human hedgehog antibody which inhibited transcription of hedgehog target genes and osteoblast differentiation of C3H10T1/2 cells. MEDI-5304 represents a potent dual hedgehog inhibitor suitable for continued development to evaluate efficacy and safety in human patients with tumors harboring elevated levels of SHH or IHH.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (EFO-21, GAMG, OE19, RT4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164690-SHH/subcellular
❮
❯
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Tumors
Product Property
- Purity
- >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
- Storage
- 4 °C, -20°C if preferred
Target
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for AFC-544CL. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Related Signaling Pathways
JAK-STAT Signaling Pathway
Related Diseases
Pancreatic Cancer
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "SHH"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-902 | Recombinant Anti-human SHH Antibody | ELISA, WB, Neut, FuncS | IgG |
| HPAB-0710-CN | Human Anti-SHH Recombinant Antibody (clone 3H8) | ELISA, FC | Human IgG2 |
| HPAB-N0236-YC | Mouse Anti-SHH Recombinant Antibody (HPAB-N0236-YC) | ELISA, FC, WB, FuncS, Inhib, IF | Mouse IgG |
| VS3-XY1420 | Mouse Anti-SHH Recombinant Antibody (clone 5H4) | ELISA, WB, FC, IHC | Mouse IgG1 |
| VS3-XY1421 | Mouse Anti-SHH Recombinant Antibody (clone 8G3) | ELISA, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-902-S(P) | Recombinant Anti-human SHH Antibody scFv Fragment | IP, IF, Biosensors, FuncS | scFv |
| MHH-902-S(P) | Recombinant Human Anti-human SHH Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
| PSBL-696 | Mouse Anti-SHH Recombinant Antibody (clone 5E1); scFv Fragment | Neut | Mouse scFv |
| HPAB-0710-CN-S(P) | Human Anti-SHH Recombinant Antibody (clone 3H8); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-0711-CN-S(P) | Human Anti-SHH Recombinant Antibody (clone 6D7OP); scFv Fragment | ELISA, FC, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-902-F(E) | Recombinant Human Anti-human SHH Antibody Fab Fragment | WB, FC, FuncS | Fab |
| HPAB-0710-CN-F(E) | Human Anti-SHH Recombinant Antibody (clone 3H8); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0711-CN-F(E) | Human Anti-SHH Recombinant Antibody (clone 6D7OP); Fab Fragment | ELISA, FC, Neut | Human Fab |
| HPAB-0712-CN-F(E) | Human Anti-SHH Recombinant Antibody (clone 3H8OP); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-N0236-YC-F(E) | Mouse Anti-SHH Recombinant Antibody; Fab Fragment (HPAB-N0236-YC-F(E)) | ELISA, FC, WB, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-566CL | Anti-Human SHH Recombinant Antibody (MEDI-5304) | Inhib | Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1955CQ | Recombinant Rat Anti-Shh Antibody (6K12) | IHC, Neut, WB | IgG2 |
| NEUT-1956CQ | Recombinant Rat Anti-Shh Antibody (CBL167) | IHC, Neut, WB | IgG2 |
| NEUT-1957CQ | Recombinant Rat Anti-Shh Antibody (CBL886) | Neut, WB | IgG2a |
| NEUT-1958CQ | Recombinant Mouse Anti-SHH Antibody (171018) | IHC-FoFr, WB, IHC-Fr, Neut, ELISA, ICC, IF | IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3261 | Hi-Affi™ Recombinant Rabbit Anti-SHH Monoclonal Antibody (DS3261AB) | FC, IHC-P, IP, WB | IgG |
| MOR-4739 | Hi-Affi™ Recombinant Rabbit Anti-SHH Monoclonal Antibody (TH253DS) | WB, IF, ICC, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-082CN | Human Anti-SHH Recombinant Antibody (clone 6D7) | ELISA, FC | Human IgG2 |
| NS-082CN-F(E) | Human Anti-SHH Recombinant Antibody (clone 6D7); Fab Fragment | ELISA, FC | Human Fab |
| NS-082CN-S(P) | Human Anti-SHH Recombinant Antibody (clone 6D7); scFv Fragment | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY476 | Mouse Anti-NHP SHH Recombinant Antibody (clone 5H4) | WB, IHC, FC, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2063 | Anti-SHH Immunohistochemistry Kit | IHC | |
| VS-0525-XY6566 | Anti-Mouse SHH Immunohistochemistry Kit | IHC | |
| VS-0525-XY6567 | Anti-Monkey SHH Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, Inhib, FuncS
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
