Anti-Human TNFRSF10A Recombinant Antibody (4H6.17.8) (CAT#: TAB-161CQ)
This antibody specifically binds to DR4 and is capable of inducing apoptosis, and capable of blocking DR4. The antibody is a blocking DR4 antibody.
Specific Inquiry
FC
Figure 1 The FACS analysis of two anti-DR4 antibodies, 4E7.24.3 ("4E7") and 4H6.17.8 ("4H6") (illustrated by the bold lines) as compared to IgG controls (dotted lines).
Both antibodies recognized the DR4 receptor expressed in human 9D cells.
ELISA
Figure 2 Results of an ELISA testing binding of DR4 antibodies, 4E7.24.3 and 4H6.17.8, to DR4 and to other known Apo-2L receptors referred to as Apo-2, DcR1, and DcR2.
Specifications
- Immunogen
- A soluble DR4 ECD
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- 4H6.17.8
- Applications
- FC, ELISA, Block
- Related Disease
- Lupus, and herpes virus infection
Applications
- Application Notes
- This antibody has been tested for use in Flow Cytometry, ELISA, Blocking. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- TNFRSF10A; tumor necrosis factor receptor superfamily, member 10a; DR4; APO2; CD261; TRAILR1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; TRAIL-R1; TRAIL receptor 1; death receptor 4; cytotoxic TRAIL receptor; TNF-related apoptosis-inducing ligand receptor 1; tumor necrosis factor receptor superfamily member 10a variant 2
- Gene ID
- 8797
- UniProt ID
- O00220
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1242z | Mouse Anti-TNFRSF10A Recombinant Antibody (clone 27A12) | WB, FC, IHC, Neut | Mouse IgG1 |
| HPAB-0460-WJ | Mouse Anti-TNFRSF10A Recombinant Antibody (HPAB-0460-WJ) | ELISA, FuncS | Mouse IgG1, λ |
| HPAB-0461-WJ | Human Anti-TNFRSF10A Recombinant Antibody (HPAB-0461-WJ) | ELISA, FuncS | Humanized IgG |
| HPAB-0412-YJ | Mouse Anti-TNFRSF10A Recombinant Antibody (HPAB-0412-YJ) | ELISA, FuncS, FC | Mouse IgG |
| HPAB-0413-YJ | Human Anti-TNFRSF10A Recombinant Antibody (HPAB-0413-YJ) | ELISA, FuncS, FC | Chimeric (Mouse/Human) IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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