Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-1324); Fab Fragment

Name: Human Anti-TNFRSF12A Recombinant Antibody (clone TPP-1324); Fab Fragment
SKU: HPAB-0055-LSX-F(E)
Rating: 5 (1 reviews)

CAT#: HPAB-0055-LSX-F(E)

Recombinant monoclonal antibody to TWEAKR. Clone TPP-1324 is a humanized antibody that can be potentially used in the treatment of tumors and other disorders and conditions associated with expression of the TWEAKR.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/if_selected.jpg

Normal Tissue Figure 2 Cerebral cortex

nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_B_7_5.jpg

Normal Tissue Figure 3 Liver

Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_9_4.jpg

Normal Tissue Figure 4 Kidney

Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_9_5.jpg

Normal Tissue Figure 5 Testis

Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_4_6.jpg

Normal Tissue Figure 6 Placenta

Trophoblastic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_2_7.jpg

Normal Tissue Figure 7 Lymph node

Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7853/21168_A_8_8.jpg

RNA Expression Figure 8 RNA cell line category: Cell line enhanced (U-251 MG)

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000006327-TNFRSF12A

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Specifications

Immunogen
Dimeric Fc-fused extracellular domains of human and murine TWEAK

Host Species
Human

Derivation
Humanized

Type
Humanized Fab

Specificity
Human TNFRSF12A

Species Reactivity
Human

Clone
TPP-1324

Applications
ELISA, WB, FC

Related Disease
Tumors and other disorders and conditions associated with expression of the TWEAKR

Product Property

Purity
>95% as determined by SDS-PAGE and HPLC analysis

Concentration
Please refer to the vial label for the specific concentration.

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
FN14; CD266; TWEAKR

Gene ID
51330

UniProt ID
Q9NP84

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-0055-LSX-F(E).pdf

MSDS

MSDS - HPAB-0055-LSX-F(E).pdf

COA

Certificate of Analysis Lookup

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