Recombinant Mouse Anti-WNV E protein Antibody Fab Fragment (E53) (CAT#: PFBW-147)
Recombinant Mouse Antibody (E53) Fab Fragment is specific to WNV E protein, expressed in Chinese Hamster Ovary cells (CHO). E53, a highly cross-reactive fusion-loop antibodies, bind to a conserved region of the flavivirus E protein and are generally weakly neutralizing. Because of their cross-reactivity, fusion-loop antibodies generated during a primary DENV infection should bind to partially or mostly immature viruses produced during a secondary infection. Therefore, these fusion-loop antibodies may promote ADE of infection by augmenting attachment and/or entry of partially immature virions. Indeed, it has been shown recently that fusion-loop-specific MAbs promote ADE in animals.
Specific Inquiry
Specifications
- Immunogen
- WNV E protein
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Fab
- Specificity
- Tested positive against native WNV E protein
- Species Reactivity
- WNV, DENV
- Clone
- E53
- Applications
- Can be useful in applications such as: Neutralization
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- WNV; West Nile virus; West Nile Fever; E; E protein
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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ScFv Antibody Products
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Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBW-146 | Recombinant Mouse Anti-DENV E protein Antibody Fab Fragment (E53) | Neut | Fab |
| HPAB-M0502-YC-S(P) | Recombinant Humanized Anti-E Protein Antibody scFv Fragment (ZA-3/2) | ELISA, Neut, FuncS | Humanized scFv |
| HPAB-M0254-YC-S(P) | Recombinant Humanized Anti-E Protein Antibody scFv Fragment (Z6) | FC, Neut | Humanized scFv |
| HPAB-M0258-YC-S(P) | Recombinant Humanized Anti-E Protein Antibody scFv Fragment (Z5) | FC, Neut | Humanized scFv |
| HPAB-M0259-YC-S(P) | Recombinant Humanized Anti-E Protein Antibody scFv Fragment (Z7) | FC, Neut | Humanized scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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