Recombinant Mouse Anti-WNV E protein Antibody Fab Fragment (E53) (CAT#: PFBW-147)
Recombinant Mouse Antibody (E53) Fab Fragment is specific to WNV E protein, expressed in Chinese Hamster Ovary cells (CHO). E53, a highly cross-reactive fusion-loop antibodies, bind to a conserved region of the flavivirus E protein and are generally weakly neutralizing. Because of their cross-reactivity, fusion-loop antibodies generated during a primary DENV infection should bind to partially or mostly immature viruses produced during a secondary infection. Therefore, these fusion-loop antibodies may promote ADE of infection by augmenting attachment and/or entry of partially immature virions. Indeed, it has been shown recently that fusion-loop-specific MAbs promote ADE in animals.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Specifications
- Immunogen
- WNV E protein
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Fab
- Specificity
- Tested positive against native WNV E protein
- Species Reactivity
- WNV, DENV
- Clone
- E53
- Applications
- Can be useful in applications such as: Neutralization
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- WNV; West Nile virus; West Nile Fever; E; E protein
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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ScFv Antibodies
Fab Antibodies
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Biparatopic Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0001-YC-S(P) | Recombinant Human Anti-E protein Antibody scFv Fragment (7A) | ELISA, WB, Neut, IP | Human scFv |
| FAMAB-0111CQ-S(P) | Recombinant Human Anti-E protein Antibody scFv Fragment (82.11) | ELISA, Neut | Human scFv |
| FAMAB-0112CQ-S(P) | Recombinant Human Anti-E protein Antibody scFv Fragment (87.1) | ELISA, Neut | Human scFv |
| FAMAB-0113CQ-S(P) | Recombinant Mouse Anti-E protein Antibody scFv Fragment (E18) | ELISA, Neut | Mouse scFv |
| FAMAB-0114CQ-S(P) | Recombinant Mouse Anti-E protein Antibody scFv Fragment (E28) | ELISA, Neut | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
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