Recombinant Mouse Anti-WNV E protein Antibody scFv Fragment (E53) (CAT#: PSBW-147)
Recombinant Mouse Antibody (E53) scFv Fragment is specific to WNV E protein, expressed in E. coli. E53, a highly cross-reactive fusion-loop antibodies, bind to a conserved region of the flavivirus E protein and are generally weakly neutralizing. Because of their cross-reactivity, fusion-loop antibodies generated during a primary DENV infection should bind to partially or mostly immature viruses produced during a secondary infection. Therefore, these fusion-loop antibodies may promote ADE of infection by augmenting attachment and/or entry of partially immature virions. Indeed, it has been shown recently that fusion-loop-specific MAbs promote ADE in animals.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Specifications
- Immunogen
- WNV E protein
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- scFv
- Specificity
- Tested positive against native WNV E protein
- Species Reactivity
- WNV, DENV
- Clone
- E53
- Applications
- Can be useful in applications such as: Neutralization
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- WNV; West Nile virus; West Nile Fever; E; E protein
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Fab Antibodies
IgG Antibodies
ScFv Antibodies
Biparatopic Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBW-146 | Recombinant Mouse Anti-DENV E protein Antibody scFv Fragment (E53) | Neut | scFv |
| HPAB-M0502-YC-F(E) | Recombinant Humanized Anti-E Protein Antibody Fab Fragment (ZA-3/2) | ELISA, Neut, FuncS | Humanized Fab |
| HPAB-M0057-YC-F(E) | Recombinant Human Anti-E Protein Antibody Fab Fragment (Z3L1) | ELISA, FC, Neut | Human Fab |
| HPAB-M0058-YC-F(E) | Recombinant Human Anti-E Protein Antibody Fab Fragment (Z20) | ELISA, FC, Neut | Human Fab |
| HPAB-M0059-YC-F(E) | Recombinant Human Anti-E Protein Antibody Fab Fragment (Z23) | ELISA, FC, Neut | Human Fab |
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