I-Ab/Mouse MOG (MEVGWYRSPFSRVVHLYRNGK) MHC Tetramer, APC (CAT#: MHC-LC661)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of MOG-derived peptide of MEVGWYRSPFSRVVHLYRNGK sequence covering 35-55 and I-Ab molecule. The pMHC tetramer recognizes mouse CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.

Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue

Specifications

  • Allele
  • I-Ab
  • Class
  • Class II
  • MHC Species
  • Mouse
  • Antigen
  • MOG
  • Antigen Species
  • Mouse
  • Peptide
  • MEVGWYRSPFSRVVHLYRNGK
  • Range
  • 35-55
  • Conjugate
  • APC
  • Application
  • FC

Target

  • Antigen Introduction
  • The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Alternative Names
  • MOG; Myelin-oligodendrocyte glycoprotein precursor; BTN6; BTNL11; MOGIG2; NRCLP7

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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