Human Anti-MOG (clone h8-18C5) scFv-Fc Chimera (CAT#: VS-0325-FY157)
Anti-MOG scFv-Fc is a recombinant antibody that binds to myelin oligodendrocyte glycoprotein (MOG). It can be used to study autoreactive immune responses against MOG in multiple sclerosis (MS) and MOG-antibody-associated disease (MOGAD).
Specific Inquiry
Normal Tissue
Figure 1 IHC staining of human cerebral cortex
(High expression. RNA expression: 73.8 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/ihc_selected.jpg
(High expression. RNA expression: 73.8 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/ihc_selected.jpg
Figure 2 IHC staining of human pancreas
(Low expression. RNA expression: 0.0 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_1_3_val_selected.jpg
(Low expression. RNA expression: 0.0 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_1_3_val_selected.jpg
Figure 3 Colon
(Mucosal lymphoid cells
Staining: Low
Intensity: Moderate
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_9_3.jpg
(Mucosal lymphoid cells
Staining: Low
Intensity: Moderate
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_9_3.jpg
Figure 4 Testis
(Leydig cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_4_6.jpg
(Leydig cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_4_6.jpg
Specifications
- Immunogen
- Human MOG
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- The scFv-Fc is designed to bind human MOG.
- Species Reactivity
- Human
- Clone
- h8-18C5
- Applications
- Flow Cytometry, ELISA
- Related Disease
- MOG-antibody-associated disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Flow Cytometry: 5 µg/mL
ELISA: 1 µg/mL
Target
- Alternative Names
- Myelin Oligodendrocyte Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; MOG Ig-AluB; MOG Alpha-5; MOG AluA; MOG AluB
- Gene ID
- 4340
- UniProt ID
- Q16653
- Long Name
- Myelin Oligodendrocyte Glycoprotein
- Sequence Similarities
- Belongs to the immunoglobulin superfamily. BTN/MOG family.
- Cellular Localization
- Cell membrane
- Protein Refseq
- NP_001008229.1; NP_001008230.1; NP_001163889.1; NP_001350539.1; NP_002424.3
- Function
- Mediates homophilic cell-cell adhesion.
Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication.
(Microbial infection) Acts as a receptor for rubella virus.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone h8-18C5"
- FAMAB-0006WJ-F(E)
- Chimeric (mouse/human) Anti-MOG Recombinant Antibody (clone h8-18C5); Fab Fragment
See other products for "MOG"
Select a product category from the dropdown menu below to view related products.
Please select product type
Fab Antibody Products
ScFv Antibody Products
IgG Antibody Products
MHC Tetramer Products for Virology
Rabbit Monoclonal Antibody Products
MHC Tetramer Products for Cancer
MHC Tetramer Products for Other Applications
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-670-F(E) | Recombinant Anti-human MOG Antibody Fab Fragment | Neut, IF, FuncS | Fab |
| PFBZ-152 | Mouse Anti-MOG Recombinant Antibody (clone 8-18C5); Fab Fragment | WB | Mouse Fab |
| FAMAB-0006WJ-F(E) | Chimeric (mouse/human) Anti-MOG Recombinant Antibody (clone h8-18C5); Fab Fragment | ELISA | Chimeric (mouse/human) Fab |
| FAMAB-0228JF-F(E) | Monkey Anti-MOG Recombinant Antibody (clone M12E); Fab Fragment | ELISA, FuncS | Monkey Fab |
| FAMAB-0229JF-F(E) | Monkey Anti-MOG Recombinant Antibody (clone M3-24); Fab Fragment | ELISA, FuncS | Monkey Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0325-FY157. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: ELISA, IHC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: ELISA, WB, BLI, SPR
Application: SPR, Inhib, FuncS
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, IF, IP, FC, FuncS
Application: ELISA, Block, WB, FC, IP
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
