Mouse Anti-MOG Recombinant Antibody (clone 8-18C5); Fab Fragment (CAT#: PFBZ-152)
Recombinant mouse Antibody (8-18C5) is capable of binding to rat Mog. The antibody 8-18C5 binds to three loops located at the membrane-distal side of MOG with a surprisingly dominant contribution made by MOG residues 101–108 containing a strained loop that forms the upper edge of the putative ligand binding site.
Specific Inquiry
Normal Tissue
Figure 1 IHC staining of human cerebral cortex
(High expression. RNA expression: 73.8 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/ihc_selected.jpg
(High expression. RNA expression: 73.8 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/ihc_selected.jpg
Figure 2 IHC staining of human pancreas
(Low expression. RNA expression: 0.0 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_1_3_val_selected.jpg
(Low expression. RNA expression: 0.0 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_1_3_val_selected.jpg
Figure 3 Colon
(Mucosal lymphoid cells
Staining: Low
Intensity: Moderate
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_9_3.jpg
(Mucosal lymphoid cells
Staining: Low
Intensity: Moderate
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_9_3.jpg
Figure 4 Testis
(Leydig cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_4_6.jpg
(Leydig cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_4_6.jpg
Specifications
- Immunogen
- Rat myelin oligodendrocyte glycoprotein
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse Fab
- Specificity
- Rat MOG
- Species Reactivity
- Rat
- Clone
- 8-18C5
- Applications
- WB
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-670 | Recombinant Anti-human MOG Antibody | WB, FC, FuncS | IgG |
| MHH-670 | Recombinant Human Anti-human MOG Antibody | IF, Neut, FuncS | IgG |
| HPAB-1774-FY | Human Anti-MOG Recombinant Antibody (clone AB138) | Neut | Human IgG1 |
| FAMAB-0006WJ | Chimeric (mouse/human) Anti-MOG Recombinant Antibody (clone h8-18C5) | IF, FC, ELISA | Chimeric (mouse/human) IgG |
| VS3-FY1783 | Rabbit Anti-MOG Recombinant Antibody (clone R09-6I4) | WB, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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