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MOG

Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Predicted to act upstream of or within cell adhesion. Located in myelin sheath. Is expressed in brain and cerebellum. Human ortholog(s) of this gene implicated in multiple sclerosis; narcolepsy; and optic neuritis. Orthologous to human MOG (myelin oligodendrocyte glycoprotein).
Protein class

Disease related genes, Human disease related genes

Predicted location

Membrane

Single cell type specificity

Cell type enriched (Oligodendrocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

Homodimer (By similarity). May form heterodimers between the different isoforms (By similarity). (Microbial infection) Interacts with rubella virus E2 glycoprotein.

Molecular function

Host cell receptor for virus entry, Receptor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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