Recombinant Human Anti-human MOG Antibody scFv Fragment
CAT#: MHH-670-S(P)
Recombinant Human Antibody scFv Fragment exhibits selective binding affinity to Human MOG, expressed in E. coli.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human cerebral cortex
High expression. RNA expression: 73.8 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/ihc_selected.jpg
Normal Tissue
Figure 2 IHC staining of human pancreas
Low expression. RNA expression: 0.0 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_1_3_val_selected.jpg
Normal Tissue
Figure 3 Colon
Mucosal lymphoid cells
Staining: Low
Intensity: Moderate
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_9_3.jpg
Normal Tissue
Figure 4 Testis
Leydig cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_4_6.jpg
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Specifications
- Immunogen
- Human myelin oligodendrocyte glycoprotein
- Host Species
- Human
- Derivation
- Human
- Type
- scFv
- Specificity
- Tested positive against native Human myelin oligodendrocyte glycoprotein
- Species Reactivity
- Human
- Applications
- Formats of immunological tests: Flow Cytometry; Enzyme-linked Immunosorbent Assay; Functional Study
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.
Target
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Ideal for Flow Cytometry
We needed an antibody to detect MOG on the cell surface using flow cytometry. This scFv fragment was perfect for our needs. Its small size might have helped in better binding and detection. The results were accurate and reproducible.
Easy to Use
The antibody came with clear instructions and was straightforward to include in our protocols. We didn't experience any issues integrating it into our experiments. It's user-friendly, even for those new to this type of research.
Effective in ELISA
We used this antibody in ELISA assays to quantify MOG levels. It provided accurate and sensitive detection, which was essential for our studies. The results were consistent, and the assay was easy to perform.
Q&As
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What is the target of this antibody?
A: This antibody specifically targets the human Myelin Oligodendrocyte Glycoprotein (MOG). MOG is a protein found on the outer surface of myelin sheaths in the central nervous system. By targeting MOG, this antibody helps researchers study myelin formation and function.
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Is this antibody useful for demyelination research?
A: Yes, since MOG is involved in the myelination process, this antibody is valuable for studying demyelination in neurological research. It helps investigate how myelin is damaged or lost in certain conditions.
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What is the format of this antibody?
A: This antibody is a recombinant human single-chain variable fragment (scFv). It's produced in E. coli, ensuring consistency and high purity. The scFv format makes it smaller and may improve tissue penetration in experiments.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "MOG"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-670-F(E) | Recombinant Anti-human MOG Antibody Fab Fragment | Neut, IF, FuncS | Fab |
| MHH-670-F(E) | Recombinant Human Anti-human MOG Antibody Fab Fragment | WB, Dot, FuncS | Fab |
| PFBZ-152 | Mouse Anti-MOG Recombinant Antibody (clone 8-18C5); Fab Fragment | WB | Mouse Fab |
| HPAB-1774-FY-S(P) | Human Anti-MOG Recombinant Antibody (clone AB138); Fab Fragment | Neut | Chimeric (marmoset/human) Fab |
| FAMAB-0228JF-F(E) | Monkey Anti-MOG Recombinant Antibody (clone M12E); Fab Fragment | ELISA, FuncS | Monkey Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-670-S(P) | Recombinant Anti-human MOG Antibody scFv Fragment | Neut, WB, FuncS | scFv |
| PSBZ-152 | Mouse Anti-MOG Recombinant Antibody (clone 8-18C5); scFv Fragment | WB | Mouse scFv |
| HPAB-1774-FY-F(E) | Monkey Anti-MOG Recombinant Antibody (clone AB138); scFv Fragment | Neut | Mouse scFv |
| FAMAB-0228JF-S(P) | Monkey Anti-MOG Recombinant Antibody (clone M12E); scFv Fragment | ELISA, FuncS | Monkey scFv |
| FAMAB-0229JF-S(P) | Monkey Anti-MOG Recombinant Antibody (clone M3-24); scFv Fragment | ELISA, FuncS | Monkey scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABZ-152 | Mouse Anti-MOG Recombinant Antibody (clone 8-18C5) | WB | Mouse IgG1 |
| FAMAB-1470CQ | Human Anti-MOG Recombinant Antibody (clone M3-24) | ELISA | Human IgG1 |
| FAMAB-1471CQ | Human Anti-MOG Recombinant Antibody (clone M38) | ELISA | Human IgG1 |
| FAMAB-1472CQ | Human Anti-MOG Recombinant Antibody (clone M3-31) | ELISA | Human IgG1 |
| FAMAB-1473CQ | Human Anti-MOG Recombinant Antibody (clone M3-8) | ELISA | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC661 | I-Ab/Mouse MOG (MEVGWYRSPFSRVVHLYRNGK) MHC Tetramer, APC | FC | |
| MHC-LC702 | I-Ab/Mouse MOG (MEVGWYRSPFSRVVHLYRNGK) MHC Tetramer, PE | FC | |
| MHC-LC926 | IAb/Mouse MOG (MEVGWYRSPFSRVVHLYRNGK) MHC Monomer | MHC Multimer | |
| MHC-YF1586 | BV421-H-2 IAb/Mouse MOG (GWYRSPFSRVVH) MHC Tetramer | FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2266 | Hi-Affi™ Recombinant Rabbit Anti-MOG Monoclonal Antibody (DS2266AB) | WB, IHC, ICC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC900 | AbPlus™ Anti-Mog Magnetic Beads (VS-0724-YC900) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY157 | Human Anti-MOG (clone h8-18C5) scFv-Fc Chimera | FC, ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC509 | Recombinant Anti-MOG Vesicular Antibody, EV Displayed (VS-0425-YC509) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4469 | Anti-Mouse MOG Immunohistochemistry Kit | IHC | |
| VS-0525-XY4470 | Anti-Rat MOG Immunohistochemistry Kit | IHC |
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