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Recombinant Anti-Human IL15 Antibody (Fc glycosylation/High-mannose glycosylated) (CAT#: Gly-198LC)

This product is a high-mannose glycosylatedd human monoclonal antibody. The antibody with enhanced ADCC specifically binds to human IL-15 and can be potentially used in the treatment of autoimmune disease.

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Subcellular Location
Figure 1 IF staining of human cell line A549
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nuclear speckles & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37738/if_selected.jpg
Figure 2 IHC staining of human lymph node
Figure 2 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in reaction center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4457/ihc_selected.jpg
Figure 3 IF staining of human cell line HeLa
Figure 3 IF staining of human cell line HeLa
(Immunofluorescent staining of human cell line HeLa shows localization to nuclear speckles & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37738/785_B10_1_red_green.jpg
Figure 4 IF staining of human cell line U-2 OS
Figure 4 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37738/783_B10_1_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Figure 5 Cerebral cortex
(Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4457/15421_B_8_5.jpg
Figure 6 Lung
Figure 6 Lung
(Macrophages
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4457/15421_A_1_4.jpg
Figure 7 Colon
Figure 7 Colon
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4457/15421_A_8_3.jpg
Figure 8 Testis
Figure 8 Testis
(Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4457/15421_A_6_6.jpg
Figure 9 Lymph node
Figure 9 Lymph node
(Germinal center cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
nuclear
Non-germinal center cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4457/15421_A_9_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (HDLM-2, Karpas-707)
Figure 10 RNA cell line category: Cell line enhanced (HDLM-2, Karpas-707)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164136-IL15
Figure 10 RNA cell line category: Cell line enhanced (HDLM-2, Karpas-707)
Figure 10 RNA cell line category: Cell line enhanced (HDLM-2, Karpas-707)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164136-IL15

Glyco-engineering

  • Glycosylation site
  • Fc region
  • Glycoform (ratio)
  • Man5 GlcNAc2
  • Glycosylation Type
  • N-glycosylation
  • Activity
  • Enhanced ADCC

Specifications

  • Target
  • IL-15 (Interleukin 15)
  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human
  • Applications
  • ELISA

Target

  • Alternative Names
  • IL15; interleukin 15; IL-15; interleukin-15
  • Related Disease
  • Autoimmune disease

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Downloads

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See other products for "IL15"

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IgG Antibody Products Rat Antibody Products ADCC Enhanced Antibody Products Humanized Antibody Products Human Antibody Products High-mannose Glycoform Antibody Products Neutralizing Antibody Products Blocking Antibody Products Rabbit Monoclonal Antibody Products Fab Antibody Products ScFv Antibody Products Non-Human Primate (NHP) Antibody Products ScFv-Fc Chimera Products
CAT Product Name Application Type
MOB-1254z Mouse Anti-IL15 Recombinant Antibody (MOB-1254z) ELISA, IHC, IP Mouse IgG
HPAB-S0072-YC Human Anti-IL15 Recombinant Antibody (clone 4H10) ELISA Human IgG
HPAB-S0073-YC Human Anti-IL15 Recombinant Antibody (clone 1H3) ELISA Human IgG
HPAB-S0074-YC Human Anti-IL15 Recombinant Antibody (clone 3C1) ELISA Human IgG
HPAB-S0075-YC Human Anti-IL15 Recombinant Antibody (clone 8C5) ELISA Human IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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