Recombinant Human Anti-BCR Antibody (CAT#: MHH-104)
Recombinant Human Antibody recognizes and binds to BCR, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-BCR mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-BCR mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38337/431_D1_2_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38337/431_D1_2_selected.jpg
Figure 2 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows membranous and cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38337/ihc_selected.jpg
(Immunohistochemical staining of human kidney shows membranous and cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38337/ihc_selected.jpg
Figure 3 IHC staining of human cerebellum
(Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18545/ihc_selected.jpg
(Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18545/ihc_selected.jpg
Figure 4 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38337/81435_B_8_5.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38337/81435_B_8_5.jpg
Figure 5 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38337/81435_A_8_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38337/81435_A_8_3.jpg
Figure 6 Kidney
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38337/81435_A_8_5.jpg
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38337/81435_A_8_5.jpg
Figure 7 RNA cell line category: Cell line enhanced (K-562)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186716-BCR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186716-BCR
Specifications
- Immunogen
- B-cell receptor
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native B-cell receptor
- Applications
- Antibody assay: Enzyme-linked Immunosorbent Assay; Immunoprecipitation; Functional Study
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- 4°C, -20°C if preferred
Target
- Alternative Names
- BCR; B-cell receptor
Related Resources
Asthma
Systemic Lupus Erythematosus
Allograft Rejection
Autoimmune Thyroid Disease
Amyotrophic Lateral Sclerosis
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-104 | Recombinant Anti-BCR Antibody | ELISA, WB, IP, FuncS | IgG |
| HPAB-0267-YC | Human Anti-BCR Recombinant Antibody (HPAB-0267-YC) | ELISA | Chimeric (mouse/human) IgG |
| HPAB-0268-YC | Human Anti-BCR Recombinant Antibody (HPAB-0268-YC) | ELISA | Humanized IgG |
| VS3-WK119 | Mouse Anti-BCR Recombinant Antibody (clone G12-E11) | WB, ELISA | Mouse IgG1 |
| VS3-FY1975 | Rabbit Anti-BCR Recombinant Antibody (clone R02-6I0) | WB, IHC-P, IP | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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