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    Recombinant Human Anti-human SYK Antibody (CAT#: MHH-937)

    Recombinant Human Antibody exhibits selective binding affinity to Human SYK, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-SYK mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-SYK mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line HEK 293
    Figure 1 IF staining of human cell line HEK 293
    (Immunofluorescent staining of human cell line HEK 293 shows localization to plasma membrane & cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1384/1472_A1_6_selected.jpg
    Normal Tissue
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Glial cells
    Staining: Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7773/18512_B_9_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Glandular cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7773/18512_A_8_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Cholangiocytes
    Staining: Low
    Intensity: Weak
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7773/18512_A_9_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Collecting ducts
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Distal tubules
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7773/18512_A_7_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Sertoli cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7773/18512_A_6_6.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7773/18512_A_7_8.jpg
    Figure 8 Tonsil
    Figure 8 Tonsil
    (Germinal center cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Squamous epithelial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7773/18512_A_6_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enhanced (Daudi, HEL, HL-60, HMC-1, REH, THP-1, U-698, U-937)
    Figure 9 RNA cell line category: Cell line enhanced (Daudi, HEL, HL-60, HMC-1, REH, THP-1, U-698, U-937)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000165025-SYK/subcellular

    Specifications

    • Immunogen
    • Human spleen tyrosine kinase
    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • IgG
    • Specificity
    • Tested positive against native Human spleen tyrosine kinase
    • Species Reactivity
    • Human
    • Applications
    • Antibody assay: Enzyme-linked Immunosorbent Assay; Western blot; Dot blot; Functional Study

    Product Property

    • Purity
    • >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
    • Storage
    • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

    Target

    • Alternative Names
    • SYK; spleen tyrosine kinase; p72-Syk; tyrosine-protein kinase SYK

    Related Resources

    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "SYK"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Fab Antibody Products ScFv Antibody Products IgG Antibody Products Rabbit Monoclonal Antibody Products ScFv-Fc Chimera Products
    CAT Product Name Application Type
    MOB-937-F(E) Recombinant Anti-human SYK Antibody Fab Fragment IF, FACS, FuncS Fab
    MHH-937-F(E) Recombinant Human Anti-human SYK Antibody Fab Fragment FC, ELISA, FuncS Fab
    HPAB-0225-YC-F(E) Rabbit Anti-SYK Recombinant Antibody; Fab Fragment (HPAB-0225-YC-F(E)) IHC, FuncS Rabbit Fab

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