Recombinant Mouse Antibody binds selectively to Mouse FCGR3A.
Figure 1 Transfection/selection procedure for T cells and CD16 expression after transfection.
The windows in the dot plots spot the different lymphocytes subsets.
Ollier, J., Vivien, R., Vié, H., & Clémenceau, B. (2017). Transfection of FcγRIIIa (CD16) Alone Can Be Sufficient To Enable Human αβTCR T Lymphocytes To Mediate Antibody-Dependent Cellular Cytotoxicity. ImmunoHorizons, 1(5), 63-70.
Figure 2 Shows results from an ELISA for binding of sCD16A by CD16A binding proteins.
Figure 3 Shows results of a cell based competition assay.
The aglycosylated humanized antibodies shown compete with aglycosylated chimeric antibody for binding to CHO-K1 cells expressing the extracellular domain of CD16A.
Figure 4 Shows inhibition of binding of sCD16A to immune complexes.
Hu3G8-1.1 is an antibody with the heavy chain Hu3G8VH-1, and the light chain Hu3G8VL-1.
Figure 5 Shows ITP protection in mice injected i.v. with mAb 3G8 (0.5 μg/g) or human IVIG (1 mg/g) one hour before ch6A6 i.p. injection.
Figure 6 Shows inhibition of ch4D5 mediated antibody-dependent cell-mediated cytotoxicity (ADCC) by humanized 3G8 antibodies.
Figure 7 Show inhibition of ch4-4-20 mediated ADCC by humanized 3G8 antibodies.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
DrMAB-978 | Recombinant Mouse Anti-Human FCGR3A Antibody F(ab')2 Fragment, clone 3G8 | FC | F(ab')2 |
HPAB-M0271-YC-F(E) | Human Anti-FCGR3A Recombinant Antibody (clone M/YC-27); Fab Fragment | ELISA | Human Fab |
HPAB-N0090-YC-F(E) | Human Anti-FCGR3A Recombinant Antibody; Fab Fragment (HPAB-N0090-YC-F(E)) | FuncS | Human Fab |
HPAB-0787-FY-S(P) | Human Anti-FCGR3A Recombinant Antibody (clone A2); Fab Fragment | Cyt | Human Fab |
HPAB-0788-FY-S(P) | Human Anti-FCGR3A Recombinant Antibody (clone B2); Fab Fragment | Cyt | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NABG-063 | Recombinant Anti-Human FCGR3A VHH Single Domain Antibody | WB, ELISA, IHC, FuncS | Llama VHH |
HPAB-1025WJ | Recombinant Camelid Anti-FCGR3A Single Domain Antibody | ELISA | Camelid VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-040WM | Anti-Human FCGR3A Recombinant Antibody (hu3G8) | ELISA | Humanized Antibody |
TAB-040WM-S(P) | Anti-Human FCGR3A Recombinant Antibody scFv Fragment (hu3G8) | ELISA | Humanized Antibody |
TAB-040WM-F(E) | Anti-Human FCGR3A Recombinant Antibody Fab Fragment (hu3G8) | ELISA | Humanized Antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-041WM | Anti-Human FCGR3A Recombinant Antibody (ch3G8) | ELISA | Chimeric Antibody (human/mouse) |
TAB-041WM-S(P) | Anti-Human FCGR3A Recombinant Antibody scFv Fragment (ch3G8) | ELISA | Chimeric Antibody (human/mouse) |
TAB-041WM-F(E) | Anti-Human FCGR3A Recombinant Antibody Fab Fragment (ch3G8) | ELISA | Chimeric Antibody (human/mouse) |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-0275MC | Recombinant Mouse Anti-Human FCGR3A Antibody. | FC, IP, IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-0384CT | Recombinant Mouse anti-Human FCGR3A Monoclonal antibody (NFN-265) | FC, IP, WB | |
HPAB-M0271-YC | Human Anti-FCGR3A Recombinant Antibody (clone M/YC-27) | ELISA | Human IgG1 |
HPAB-N0090-YC | Human Anti-FCGR3A Recombinant Antibody (HPAB-N0090-YC) | FuncS | Human IgG |
HPAB-0787-FY | Human Anti-FCGR3A Recombinant Antibody (clone A2) | Cyt | Human IgG1 |
HPAB-0788-FY | Human Anti-FCGR3A Recombinant Antibody (clone B2) | Cyt | Human IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-797CQ | Mouse Anti-FCGR3A Recombinant Antibody (clone 3G8) | FC, IHC-Fr, ICC, IP, Stim, Costim, Block | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-798CQ | Mouse Anti-FCGR3A Recombinant Antibody (clone B73.1) | FC, FuncS, Neut | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1275 | Hi-Affi™ Rabbit Anti-FCGR3A Recombinant Antibody (clone DS1275AB) | WB, ICC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-M0271-YC-S(P) | Human Anti-FCGR3A Recombinant Antibody (clone M/YC-27); scFv Fragment | ELISA | Human scFv |
HPAB-N0090-YC-S(P) | Human Anti-FCGR3A Recombinant Antibody; scFv Fragment (HPAB-N0090-YC-S(P)) | FuncS | Human scFv |
HPAB-0787-FY-F(E) | Human Anti-FCGR3A Recombinant Antibody (clone A2); scFv Fragment | Cyt | Human scFv |
HPAB-0788-FY-F(E) | Human Anti-FCGR3A Recombinant Antibody (clone B2); scFv Fragment | Cyt | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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