Recombinant Human Anti-HCV Antibody Fab Fragment (HC33.4)
CAT#: PABX-071-F (E)
Anti-HCV antibody is a Human of Fab class that binds to an HCV.
Published Data
-1.png)
Figure 1 Binding properties of broadly neutralizing HMAbs.
(A) Antibody binding to wt or HVR1 recombinant E2 determined by ELISA. Recombinant H77C E2 cell lysate was captured on GNA-precoated wells. Bound proteins were incubated with each test HMAb at 1 g/ml (x axis), and bound antibody was detected. with antihuman antibody. The y axis shows the mean optical density values for triplicate wells (means from three experiments standard deviations [SD]). (B)Tabulation of difference in binding between HVR1 and wt E2 with calculated P values.
Keck, Z. Y., Girard-Blanc, C., Wang, W., Lau, P., Zuiani, A., Rey, F. A., ... & Foung, S. K. (2016). Antibody response to hypervariable region 1 interferes with broadly neutralizing antibodies to hepatitis C virus. Journal of virology, 90(6), 3112-3122.
-2.png)
Figure 2 SNAPR-values across E1E2 determined using only subtype 1a HCVpp neutralized by HC33.4 or AR4A.
The 8 positions with lowest SNAPR-values for HC33.4 and AR4A are in bold print. Previously defined HC33.4 and AR4A binding epitopes are indicated (blue and pink), as is hypervariable region 1 (HVR1) (gray).
El-Diwany, R., Cohen, V. J., Mankowski, M. C., Wasilewski, L. N., Brady, J. K., Snider, A. E., ... & Bailey, J. R. (2017). Extra-epitopic hepatitis C virus polymorphisms confer resistance to broadly neutralizing antibodies by modulating binding to scavenger receptor B1. PLoS pathogens, 13(2), e1006235.
❮
-1.webp)
-2.webp)
❯
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- Fab
- Specificity
- Tested positive against native Hepatitis C virus HCV
- Species Reactivity
- Hepatitis C virus
- Clone
- HC33. 4
- Applications
- WB 1:1000-1:5000
ELISA 1:10000-1:20000
Neut (assay dependent)
FuncS (assay dependent)
IHC(P) 1:200-1:2000
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- Assay-depended
Target
- Alternative Names
- Hepatitis C virus; HCV; HVC; Flaviviridae
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for PABX-071-F (E). Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone HC33. 4"
- CAT
- Product Name
See other products for "HCV"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-444-F(E) | Recombinant Anti-HCV Antibody Fab Fragment | WB, FACS, FuncS | Fab |
| HPAB-0802-FY-S(P) | Recombinant Anti-HCV Antibody Fab Fragment (AOT3) | E | |
| FAMAB-0024WJ-F(E) | Human Anti-HCV Recombinant Antibody (clone B12.F8); Fab Fragment | ELISA, IF, IHC | Human Fab |
| FAMAB-0025WJ-F(E) | Human Anti-HCV Recombinant Antibody (clone CM3.B6); Fab Fragment | ELISA, IF, IHC | Human Fab |
| FAMAB-0026WJ-F(E) | Human Anti-HCV Recombinant Antibody (clone E6.D10); Fab Fragment | ELISA, IF, IHC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-079 | Recombinant Anti-HCV VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-444 | Recombinant Human Anti-HCV Antibody | IF, Neut, FuncS | IgG |
| HPAB-0043LY | Recombinant Mouse Anti-HCV Antibody (PA-29) | WB | |
| FAMAB-0024WJ | Human Anti-HCV Recombinant Antibody (clone B12.F8) | ELISA, IF, IHC, WB | Human IgG |
| FAMAB-0025WJ | Human Anti-HCV Recombinant Antibody (clone CM3.B6) | ELISA, IF, IHC, WB, Inhib | Human IgG |
| FAMAB-0026WJ | Human Anti-HCV Recombinant Antibody (clone E6.D10) | ELISA, IF, IHC | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-344CL | Human Anti-HCV Recombinant Antibody (TAB-344CL) | FuncS | Human IgG |
| PABX-071 | Recombinant Human Anti-HCV Antibody (HC33.4) | WB, ELISA, Neut, FuncS | IgG |
| PABX-079 | Recombinant Human Anti-Hepatitis C virus Antibody (AP33) | WB, ELISA, FuncS | IgG |
| PABX-079-F (E) | Recombinant Human Anti-Hepatitis C virus Antibody Fab Fragment (AP33) | WB, ELISA, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-071-S (P) | Recombinant Human Anti-HCV Antibody scFv Fragment (HC33.4) | WB, ELISA, Neut, FuncS | scFv |
| PABX-079-S (P) | Recombinant Human Anti-Hepatitis C virus Antibody scFv Fragment (AP33) | WB, ELISA, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1118LY-S(P) | Humanized Anti-HCV Antibody scFv Fragment (CBL021) | ELISA, FC | |
| HPAB-1119LY-S(P) | Humanized Anti-HCV Antibody scFv Fragment (CBL022) | ELISA, FC | |
| HPAB-1120LY-S(P) | Humanized Anti-HCV Antibody scFv Fragment (CBL023) | ELISA, FC | |
| HPAB-1121LY-S(P) | Humanized Anti-HCV Antibody scFv Fragment (CBL024) | ELISA, FC | |
| HPAB-1178-FY-F(E) | Human Anti-HCV Recombinant Antibody Fab Fragment (HPAB-1178-FY-F(E)) | ELISA | Human Fab |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: WB, Neut, ELISA, IF, IP, FuncS, FC
Application: ELISA, WB, BLI, SPR
-2.png)
Application: IB, ELISA, FC, FuncS
Application: ELISA, FuncS, IHC, IF, FC, ADCC
-5.jpg)
Application: ELISA, IHC, FC, IP, IF, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
