Anti-Human AOC3 Recombinant Antibody (Timolumab) (CAT#: TAB-455CQ)
Recombinant monoclonal antibody to AOC3. Timolumab is a human monoclonal antibody that can be potentially used in the treatment of Psoriasis, Rheumatoid arthritis, Primary sclerosing cholangitis.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/980/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/980/if_selected.jpg
Figure 2 Lung
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/980/2500_A_1_4_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/980/2500_A_1_4_val_selected.jpg
Figure 3 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/980/2500_A_7_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/980/2500_A_7_3.jpg
Figure 4 Soft tissue
(Fibroblasts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25797/57908_B_2_8.jpg
(Fibroblasts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25797/57908_B_2_8.jpg
Figure 5 RNA cell line category: Cell line enriched (ASC diff)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131471-AOC3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131471-AOC3
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG4, κ
- Specificity
- Human AOC3
- Species Reactivity
- Human
- Applications
- Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Functional Studies
- Conjugate
- Unconjugated
- CAS
- 1073538-99-4
- Generic Name
- Timolumab
- UNII
- UJO03RO3K6
- Related Disease
- Psoriasis, Rheumatoid arthritis, Primary sclerosing cholangitis
Product Property
- Purity
- > 95% as determined by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
- Alternative Names
- Amine Oxidase, Copper Containing 3; Semicarbazide-Sensitive Amine Oxidase; Vascular Adhesion Protein 1; Copper Amine Oxidase; EC 1.4.3.21; VAP-1; HPAO; SSAO; VAP1; Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1); Placenta Copper Monamine Oxidase; EC 1.4.3
- Gene ID
- 8639
- UniProt ID
- Q16853
Related Resources
Please refer to Timolumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Timolumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Timolumab"
Afuco™ Anti-AOC3 ADCC Recombinant Antibody (Timolumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to AOC3. Timolumab is a human monoclonal antibody that can be potentially used in the treatment of Psoriasis, Rheumatoid arthritis, Primary sclerosing cholangitis.
See other products for "AOC3"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3906z | Mouse Anti-AOC3 Recombinant Antibody (clone 40D3) | WB, ELISA, FC, IHC, IP | Mouse IgG2a, κ |
| HPAB-1627LY | Mouse Anti-AOC3 Recombinant Antibody (clone 1G3) | ELISA | Mouse IgG |
| HPAB-1628LY | Mouse Anti-AOC3 Recombinant Antibody (clone 3F10) | ELISA | Mouse IgG |
| HPAB-1629LY | Mouse Anti-AOC3 Recombinant Antibody (clone 3G6) | ELISA | Mouse IgG |
| HPAB-0966-FY | Human Anti-AOC3 Recombinant Antibody (HPAB-0966-FY) | IF | Human IgG |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-261 | Anti-Human AOC3 Recombinant Antibody (Vapaliximab) | WB, FC, IP, ELISA, Neut, FuncS, IF | IgG2 |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-137 | Anti-Human AOC3 Recombinant Antibody (Vepalimomab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | IgM |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-045CL | Human Anti-AOC3 Recombinant Antibody (TAB-045CL) | ELISA | Human IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0189 | Hi-Affi™ Rabbit Anti-AOC3 Recombinant Antibody (clone DS189AB) | IP, IHC-P, WB | Rabbit IgG |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-098CN | Human Anti-AOC3 Recombinant Antibody (clone Mo2D10) | ELISA, FC, IF, IHC, Inhib, FuncS | Human IgG1, κ |
| NS-099CN | Human Anti-AOC3 Recombinant Antibody (clone BTT-1002) | ELISA, FC, IF, IHC, Inhib, FuncS | Human IgG |
| NS-098CN-F(E) | Human Anti-AOC3 Recombinant Antibody (clone Mo2D10); Fab Fragment | ELISA, FC, IF, IHC | Human Fab |
| NS-099CN-F(E) | Human Anti-AOC3 Recombinant Antibody (clone BTT-1002); Fab Fragment | ELISA, FC, IF, IHC | Human Fab |
| NS-098CN-S(P) | Mouse Anti-AOC3 Recombinant Antibody (clone Mo2D10); scFv Fragment | ELISA, FC, IF, IHC | Mouse scFv |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1627LY-S(P) | Mouse Anti-AOC3 Recombinant Antibody (clone 1G3); scfv Fragment | ELISA | Mouse scfv |
| HPAB-0966-FY-F(E) | Human Anti-AOC3 Recombinant Antibody; Fab Fragment (HPAB-0966-FY-F(E)) | IF | Human Fab |
| HPAB-0967-FY-F(E) | Human Anti-AOC3 Recombinant Antibody; Fab Fragment (HPAB-0967-FY-F(E)) | IF | Human Fab |
| HPAB-0968-FY-F(E) | Human Anti-AOC3 Recombinant Antibody; Fab Fragment (HPAB-0968-FY-F(E)) | IF | Human Fab |
| HPAB-0969-FY-F(E) | Human Anti-AOC3 Recombinant Antibody; Fab Fragment (HPAB-0969-FY-F(E)) | IF | Human Fab |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1627LY-F(E) | Mouse Anti-AOC3 Recombinant Antibody (clone 1G3); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0966-FY-S(P) | Human Anti-AOC3 Recombinant Antibody; scFv Fragment (HPAB-0966-FY-S(P)) | IF | Human scFv |
| HPAB-0967-FY-S(P) | Human Anti-AOC3 Recombinant Antibody; scFv Fragment (HPAB-0967-FY-S(P)) | IF | Human scFv |
| HPAB-0968-FY-S(P) | Human Anti-AOC3 Recombinant Antibody; scFv Fragment (HPAB-0968-FY-S(P)) | IF | Human scFv |
| HPAB-0969-FY-S(P) | Human Anti-AOC3 Recombinant Antibody; scFv Fragment (HPAB-0969-FY-S(P)) | IF | Human scFv |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-261 | Afuco™ Anti-AOC3 ADCC Recombinant Antibody (Vapaliximab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS | ADCC enhanced antibody |
| AFC-TAB-455CQ | Afuco™ Anti-AOC3 ADCC Recombinant Antibody (Timolumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-137 | Afuco™ Anti-AOC3 ADCC Recombinant Antibody (Vepalimomab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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