A*02:01/Human Ins B. 10 (HLVEALYLV) MHC Monomer
CAT#: MHC-YF236
This product is a MHC monomer of biotinylated peptide/MHC complex composed Ins B. 10-derived peptide of HLVEALYLV sequence and A*02:01 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.


Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- Ins B. 10
- Antigen Species
- Human
- Peptide
- HLVEALYLV
- Conjugate
- Biotin
- Application
- MHC Multimer
Target
- Antigen Introduction
- After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
- Alternative Names
- IDDM; ILPR; IRDN; IDDM1; IDDM2; MODY10
- Gene ID
- 3630
- UniProt ID
- P01308
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Related Diseases
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Datasheet
MSDS
COA
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See other products for "INS"
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FAMAB-0185-YC-S(P) | Mouse Anti-INS Recombinant Antibody (clone 125); scFv Fragment | ELISA | Mouse scFv |
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CAT | Product Name | Application | Type |
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FAMAB-0182-YC-F(E) | Mouse Anti-INS Recombinant Antibody (clone 123); Fab Fragment | ELISA | Mouse Fab |
FAMAB-0183-YC-F(E) | Mouse Anti-INS Recombinant Antibody (clone 124); Fab Fragment | ELISA | Mouse Fab |
FAMAB-0184-YC-F(E) | Mouse Anti-INS Recombinant Antibody (clone 133); Fab Fragment | ELISA | Mouse Fab |
FAMAB-0185-YC-F(E) | Mouse Anti-INS Recombinant Antibody (clone 125); Fab Fragment | ELISA | Mouse Fab |
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CAT | Product Name | Application | Type |
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MRO-1977-CN | Rabbit Anti-INS Polyclonal Antibody (MRO-1977-CN) | IHC, FC, ELISA | Rabbit IgG |
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VS3-CJ256 | Mouse Anti-INS Recombinant Antibody (VS3-CJ256) | IHC | Mouse IgG2b |
VS3-CJ257 | Rabbit Anti-INS Recombinant Antibody (VS3-CJ257) | ICC, IF, IHC | Rabbit IgG |
CAT | Product Name | Application | Type |
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CAT | Product Name | Application | Type |
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VS-0525-XY3566 | Anti-INS Immunohistochemistry Kit | IHC | |
VS-0525-XY3567 | Anti-Mouse INS Immunohistochemistry Kit | IHC | |
VS-0525-XY3568 | Anti-Rat INS Immunohistochemistry Kit | IHC |
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