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INS
Loading...Anti-INS Products
- PE-A*02:01/Human INS (ALWGPDPAAA) MHC Tetramer (MHC-LC1682)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: ALWGPDPAAA
- Conjugate: PE
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: LVEALYLVCGERGG
- Conjugate: PE
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GSLQPLALEGSLQKRG
- Conjugate: PE
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: AQWGPDPAAA
- Conjugate: BV421
- APC-A*02:01/Human INS (ALWGPDPAAA) MHC Tetramer (MHC-LC1683)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: ALWGPDPAAA
- Conjugate: APC
- APC-A*02:01/Human INS (AQWGPDPAAA) MHC Tetramer (MHC-LC906)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: AQWGPDPAAA
- Conjugate: APC
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GSLQPLALEGSLQKRG
- Conjugate: BV421
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GSLQPLALEGSLQKRG
- Conjugate: APC
- BV421-H2-K1/Human INS (LYLVCGERG) MHC Tetramer (MHC-LC979)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERG
- Conjugate: BV421
- APC-H2-K1/Human INS (LYLVCGERG) MHC Tetramer (MHC-LC978)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERG
- Conjugate: APC
- BV421-H2-K1/Human INS (LYLVCGERV) MHC Tetramer (MHC-LC982)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERV
- Conjugate: BV421
- APC-H2-K1/Human INS (LYLVCGERV) MHC Tetramer (MHC-LC981)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERV
- Conjugate: APC
- BV421-H2-K1/Human INS (LYLVCGERGF) MHC Tetramer (MHC-LC985)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERGF
- Conjugate: BV421
- APC-H2-K1/Human INS (LYLVCGERGF) MHC Tetramer (MHC-LC984)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERGF
- Conjugate: APC
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: LVEALYLVCGERGG
- Conjugate: APC
- BV421-A*02:01/Human INS (ALWGPDPAAA) MHC Tetramer (MHC-LC1684)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: ALWGPDPAAA
- Conjugate: BV421
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
- Recombinant Human Anti-INS Soluble TCR (clone FS17) (scTCR-157CQ-S(P))
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- Species Reactivity: Human
- Epitope: GSLQPLALEGSLQKRG
- MHC: HLA-DR4
- Recombinant Human Anti-INS Soluble TCR (clone FS18) (scTCR-158CQ-S(P))
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- Species Reactivity: Human
- Epitope: GSLQPLALEGSLQKRG
- MHC: HLA-DR4
- Recombinant Mouse Anti-INS Soluble TCR (clone G9C8) (scTCR-159CQ-S(P))
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- Species Reactivity: Human
- Epitope: LYLVCGERG
- MHC: H-2Kd
- Recombinant Human Anti-INS Soluble TCR (clone 1C8) (scTCR-357CQ-S(P))
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Human Anti-INS Soluble TCR (clone 1E6) (scTCR-358CQ-S(P))
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Human Anti-INS Soluble TCR (clone 3F2) (scTCR-359CQ-S(P))
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Mouse Anti-INS Recombinant Antibody (clone 5E1) (MRO-0841-CN)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, IHC
- Rabbit Anti-INS Recombinant Antibody (clone CBACN-307) (MRO-0842-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: IF, IHC
- Mouse Anti-INS Recombinant Antibody (clone A6-6) (MRO-0843-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: IHC, ELISA
- Rabbit Anti-INS Polyclonal Antibody (MRO-1977-CN) (MRO-1977-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC, FC, ELISA
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: PE
-
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: APC
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: FITC
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: Unconjugated
- Human Anti-INS Recombinant Soluble TCR (clone (1E6)-2) (scTCR-0546YC-S(P))
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- Epitope: AQWGPDPAAA
- MHC: HLA-A02
- Human Anti-INS Recombinant Soluble TCR (clone (1E6)-3) (scTCR-0547YC-S(P))
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- Species Reactivity: Human
- Epitope: RQFGPDFPTI
- MHC: HLA-A*02:01
- Human Anti-INS Recombinant Soluble TCR (clone (1E6)-4) (scTCR-0548YC-S(P))
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- Epitope: RQFGPDWIVA
- MHC: HLA-A02
- Human Anti-INS Recombinant Soluble TCR (clone (1E6)-5) (scTCR-0549YC-S(P))
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- Species Reactivity: Human
- Epitope: RQWGPDPAAV
- MHC: HLA-A*02:01
- Human Anti-INS Recombinant Antibody (clone mAb48) (HPAB-1993-FY)
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- Species Reactivity: Human
- Type: Human IgG3, κ
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
- Recombinant Human Anti-INS Soluble TCR (1C8) (C-Cys) (VS-0622-YF3064)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Human Anti-INS Soluble TCR (1E6) (C-Cys) (VS-0622-YF3065)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Human Anti-INS Soluble TCR (3F2) (C-Cys) (VS-0622-YF3066)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Mouse Anti-INS Soluble TCR (BDC12-4.1) (KIH) (VS-0622-YF7269)
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- Epitope: VEALYLVCGEEG
- MHC: H2 class II
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: LVEALYLVCGERGG
- Conjugate: BV421
-
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
- Mouse Anti-INS Recombinant Antibody (clone 123) (FAMAB-0182YC)
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- Species Reactivity: Bovine
- Type: Mouse IgG1
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 124) (FAMAB-0183YC)
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- Species Reactivity: Bovine
- Type: Mouse IgG2a
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 133) (FAMAB-0184YC)
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- Species Reactivity: Bovine
- Type: Mouse IgG2a
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 125) (FAMAB-0185YC)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 127) (FAMAB-0186YC)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 193020) (FAMAB-0187YC)
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- Species Reactivity: Mouse
- Type: Mouse IgG2b, κ
- Application: ELISA, WB
- Mouse Anti-INS Recombinant Antibody (MOB-0058F) (MOB-0058F)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
- Mouse Anti-INS Recombinant Antibody (MOB-0059F) (MOB-0059F)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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- Species Reactivity: Human, Cow, Pig
- Type: Mouse IgG1
- Application: WB, ELISA, IHC
- Recombinant Human Anti-INS Soluble TCR (1C8) (ZIP-Fos/ZIP-Jun) (VS-0622-YF356)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Human Anti-INS Soluble TCR (1E6) (ZIP-Fos/ZIP-Jun) (VS-0622-YF357)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Human Anti-INS Soluble TCR (3F2) (ZIP-Fos/ZIP-Jun) (VS-0622-YF358)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Mouse Anti-INS Soluble TCR (BDC12-4.1) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1853)
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- Epitope: VEALYLVCGEEG
- MHC: H2 class II
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- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (KIH) (VS-0622-YF7270) (VS-0622-YF7270)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (KIH) (VS-0622-YF7271) (VS-0622-YF7271)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (TA5) (KIH) (VS-0622-YF7272)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: IHC-P
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- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: IHC-P
- Mouse Anti-INS Recombinant Antibody (VS3-CJ256) (VS3-CJ256)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: IHC
- Rabbit Anti-INS Recombinant Antibody (VS3-CJ257) (VS3-CJ257)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: ICC, IF, IHC
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, IHC-Fr
- PE-H2-K1/Human INS (LYLVCGERG) MHC Tetramer (MHC-LC977)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERG
- Conjugate: PE
- PE-H2-K1/Human INS (LYLVCGERV) MHC Tetramer (MHC-LC980)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERV
- Conjugate: PE
- PE-H2-K1/Human INS (LYLVCGERGF) MHC Tetramer (MHC-LC983)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERGF
- Conjugate: PE
- PE-A*02:01/Human INS (AQWGPDPAAA) MHC Tetramer (MHC-LC905)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: AQWGPDPAAA
- Conjugate: PE
- PE-A*02:01/Human INS (HLVEALYLV) MHC Tetramer (MHC-CN0913)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: PE
- APC-A*02:01/Human INS (HLVEALYLV) MHC Tetramer (MHC-CN0914)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: APC
- FITC-A*02:01/Human INS (HLVEALYLV) MHC Tetramer (MHC-CN0915)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: FITC
- Human Anti-INS Recombinant Soluble TCR (clone (1E6)-6) (scTCR-0550YC-S(P))
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- Species Reactivity: Human
- Epitope: YLGGPDFPTI
- MHC: HLA-A*02:01
- Human Anti-INS Recombinant Antibody (clone mAb49) (HPAB-1994-FY)
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA
- A*02:01/Human Ins B. 10 (HLVEALYLV) MHC Monomer (MHC-YF236)
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- Class: Class I
- Antigen: Ins B. 10
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: Biotin
- Mouse Anti-INS Recombinant Antibody (clone CG7C7) (FAMAB-0352JF)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, FuncS
- Mouse Anti-INS Recombinant Antibody (clone CG7C7); Fab Fragment (FAMAB-0352JF-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FuncS
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- Derivation: Yeast cell surface display
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, FuncS
- Recombinant Anti-human INS VHH Single Domain Antibody (NAB-1554-VHH)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ICC, ChiP, FA, ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Human Anti-INS Recombinant Antibody (clone mAb48); Fab Fragment (HPAB-1993-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab, κ
- Application: ELISA
- Human Anti-INS Recombinant Antibody (clone mAb48); scFv Fragment (HPAB-1993-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 133); Fab Fragment (FAMAB-0184-YC-F(E))
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- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 125); Fab Fragment (FAMAB-0185-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 127); Fab Fragment (FAMAB-0186-YC-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 193020); Fab Fragment (FAMAB-0187-YC-F(E))
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- Species Reactivity: Mouse
- Type: Mouse Fab
- Application: ELISA, WB
- Mouse Anti-INS Recombinant Antibody (clone 123); scFv Fragment (FAMAB-0182-YC-S(P))
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- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 124); scFv Fragment (FAMAB-0183-YC-S(P))
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- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 133); scFv Fragment (FAMAB-0184-YC-S(P))
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- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 125); scFv Fragment (FAMAB-0185-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 127); scFv Fragment (FAMAB-0186-YC-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 193020); scFv Fragment (FAMAB-0187-YC-S(P))
-
- Species Reactivity: Mouse
- Type: Mouse scFv
- Application: ELISA, WB
- Mouse Anti-INS Recombinant Antibody (clone 123); Fab Fragment (FAMAB-0182-YC-F(E))
-
- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone 124); Fab Fragment (FAMAB-0183-YC-F(E))
-
- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P, WB
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IF, ICC, IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region.


Maturity Onset Diabetes of the Young
