INS
Anti-INS Recombinant Antibody Products
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: ALWGPDPAAA
- Conjugate: PE
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: LVEALYLVCGERGG
- Conjugate: PE
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERGF
- Conjugate: PE
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERV
- Conjugate: PE
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERG
- Conjugate: PE
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GSLQPLALEGSLQKRG
- Conjugate: PE
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: AQWGPDPAAA
- Conjugate: PE
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
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- Species Reactivity: Human
- Epitope: LYLVCGERG
- MHC: H-2Kd
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- Species Reactivity: Human
- Epitope: GSLQPLALEGSLQKRG
- MHC: HLA-DR4
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- Species Reactivity: Human
- Epitope: GSLQPLALEGSLQKRG
- MHC: HLA-DR4
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Epitope: RLLPLLALL
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
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- Epitope: VEALYLVCGEEG
- MHC: H2 class II
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- Species Reactivity: Human
- Epitope: YQFGPDFPIA
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Epitope: YLGGPDFPTI
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Epitope: RQWGPDPAAV
- MHC: HLA-A*02:01
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- Epitope: RQFGPDWIVA
- MHC: HLA-A02
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- Species Reactivity: Human
- Epitope: RQFGPDFPTI
- MHC: HLA-A*02:01
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- Epitope: AQWGPDPAAA
- MHC: HLA-A02
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- Class: Class I
- Antigen: Ins B. 10
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: Biotin
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- Class: Class II
- Antigen: Proinsulin
- Antigen Species: Human
- Peptide: GIVEQCCTSICSLYQ
- Conjugate: Biotin
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- Class: Class II
- Antigen: Proinsulin
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: Biotin
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: Unconjugated
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: FITC
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: APC
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: PE
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: Unconjugated
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: FITC
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: APC
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: PE
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: ALWGPDPAAA
- Conjugate: BV421
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: LVEALYLVCGERGG
- Conjugate: BV421
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERGF
- Conjugate: BV421
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERV
- Conjugate: BV421
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERG
- Conjugate: BV421
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GSLQPLALEGSLQKRG
- Conjugate: BV421
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: AQWGPDPAAA
- Conjugate: BV421
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: ALWGPDPAAA
- Conjugate: APC
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: LVEALYLVCGERGG
- Conjugate: APC
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERGF
- Conjugate: APC
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERV
- Conjugate: APC
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERG
- Conjugate: APC
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GSLQPLALEGSLQKRG
- Conjugate: APC
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: AQWGPDPAAA
- Conjugate: APC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, FuncS
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- Species Reactivity: Human
- Type: Human IgG3, κ
- Application: ELISA
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- Species Reactivity: Bovine
- Type: Mouse IgG1
- Application: ELISA, FuncS
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC, FC, ELISA
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: IHC, ELISA
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: IF, IHC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, IHC
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, IHC-Fr
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- Species Reactivity: Mouse
- Type: Mouse IgG2b, κ
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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- Species Reactivity: Bovine
- Type: Mouse IgG2a
- Application: ELISA
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- Species Reactivity: Bovine
- Type: Mouse IgG2a
- Application: ELISA
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- Species Reactivity: Bovine
- Type: Mouse IgG1
- Application: ELISA
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- Species Reactivity: Mouse
- Type: Mouse scFv
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FuncS
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FuncS
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- Species Reactivity: Human
- Type: Human Fab, κ
- Application: ELISA
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- Species Reactivity: Human
- Type: Human Fab, κ
- Application: ELISA
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- Species Reactivity: Human
- Type: Human Fab, κ
- Application: ELISA
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- Species Reactivity: Mouse
- Type: Mouse Fab
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ICC, ChiP, FA, ELISA
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IF, ICC, IHC
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P, WB
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For Research Use Only. Not For Clinical Use.
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]