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INS

Anti-INS Products
- Recombinant Human Anti-INS Soluble TCR (WB4) (KIH) (VS-0622-YF7278)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (WG10) (KIH) (VS-0622-YF7279)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: IHC-P
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- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: IHC-P
- Mouse Anti-INS Recombinant Antibody (VS3-CJ256) (VS3-CJ256)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: IHC
- Rabbit Anti-INS Recombinant Antibody (VS3-CJ257) (VS3-CJ257)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: ICC, IF, IHC
- Recombinant Human Anti-INS Soluble TCR (TA5) (KIH) (VS-0622-YF7272)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (TA6) (KIH) (VS-0622-YF7273)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (TC6) (KIH) (VS-0622-YF7274)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (UB6) (KIH) (VS-0622-YF7275)
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- Species Reactivity: Human
- Epitope: RLLPLLALL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (VC4) (KIH) (VS-0622-YF7276)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (VD4) (KIH) (VS-0622-YF7277)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (1C8) (KIH) (VS-0622-YF5772)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Human Anti-INS Soluble TCR (1E6) (KIH) (VS-0622-YF5773)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Human Anti-INS Soluble TCR (3F2) (KIH) (VS-0622-YF5774)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Mouse Anti-INS Soluble TCR (BDC12-4.1) (KIH) (VS-0622-YF7269)
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- Epitope: VEALYLVCGEEG
- MHC: H2 class II
- Recombinant Human Anti-INS Soluble TCR (KIH) (VS-0622-YF7270) (VS-0622-YF7270)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (KIH) (VS-0622-YF7271) (VS-0622-YF7271)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (VD4) (C-Cys) (VS-0622-YF4569)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (WB4) (C-Cys) (VS-0622-YF4570)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (WG10) (C-Cys) (VS-0622-YF4571)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (FS17) (KIH) (VS-0622-YF5573)
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- Species Reactivity: Human
- Epitope: GSLQPLALEGSLQKRG
- MHC: HLA-DR4
- Recombinant Human Anti-INS Soluble TCR (FS18) (KIH) (VS-0622-YF5574)
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- Species Reactivity: Human
- Epitope: GSLQPLALEGSLQKRG
- MHC: HLA-DR4
- Recombinant Mouse Anti-INS Soluble TCR (G9C8) (KIH) (VS-0622-YF5575)
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- Species Reactivity: Human
- Epitope: LYLVCGERG
- MHC: H-2Kd
- Recombinant Human Anti-INS Soluble TCR (C-Cys) (VS-0622-YF4563) (VS-0622-YF4563)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (TA5) (C-Cys) (VS-0622-YF4564)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (TA6) (C-Cys) (VS-0622-YF4565)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (TC6) (C-Cys) (VS-0622-YF4566)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (UB6) (C-Cys) (VS-0622-YF4567)
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- Species Reactivity: Human
- Epitope: RLLPLLALL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (VC4) (C-Cys) (VS-0622-YF4568)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Mouse Anti-INS Soluble TCR (G9C8) (C-Cys) (VS-0622-YF2867)
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- Species Reactivity: Human
- Epitope: LYLVCGERG
- MHC: H-2Kd
- Recombinant Human Anti-INS Soluble TCR (1C8) (C-Cys) (VS-0622-YF3064)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Human Anti-INS Soluble TCR (1E6) (C-Cys) (VS-0622-YF3065)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Human Anti-INS Soluble TCR (3F2) (C-Cys) (VS-0622-YF3066)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Mouse Anti-INS Soluble TCR (BDC12-4.1) (C-Cys) (VS-0622-YF4561)
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- Epitope: VEALYLVCGEEG
- MHC: H2 class II
- Recombinant Human Anti-INS Soluble TCR (C-Cys) (VS-0622-YF4562) (VS-0622-YF4562)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (VC4) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1860)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (VD4) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1861)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (WB4) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1862)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (WG10) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1863)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (FS17) (C-Cys) (VS-0622-YF2865)
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- Species Reactivity: Human
- Epitope: GSLQPLALEGSLQKRG
- MHC: HLA-DR4
- Recombinant Human Anti-INS Soluble TCR (FS18) (C-Cys) (VS-0622-YF2866)
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- Species Reactivity: Human
- Epitope: GSLQPLALEGSLQKRG
- MHC: HLA-DR4
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- Species Reactivity: Human, Cow, Pig
- Type: Mouse IgG1
- Application: WB, ELISA, IHC
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- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
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- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (TA5) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1856)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (TA6) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1857)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (TC6) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1858)
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- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (UB6) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1859)
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- Species Reactivity: Human
- Epitope: RLLPLLALL
- MHC: HLA-A*02:01
- Recombinant Human Anti-INS Soluble TCR (FS18) (ZIP-Fos/ZIP-Jun) (VS-0622-YF158)
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- Species Reactivity: Human
- Epitope: GSLQPLALEGSLQKRG
- MHC: HLA-DR4
- Recombinant Mouse Anti-INS Soluble TCR (G9C8) (ZIP-Fos/ZIP-Jun) (VS-0622-YF159)
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- Species Reactivity: Human
- Epitope: LYLVCGERG
- MHC: H-2Kd
- Recombinant Human Anti-INS Soluble TCR (1C8) (ZIP-Fos/ZIP-Jun) (VS-0622-YF356)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Human Anti-INS Soluble TCR (1E6) (ZIP-Fos/ZIP-Jun) (VS-0622-YF357)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Human Anti-INS Soluble TCR (3F2) (ZIP-Fos/ZIP-Jun) (VS-0622-YF358)
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- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
- Recombinant Mouse Anti-INS Soluble TCR (BDC12-4.1) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1853)
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- Epitope: VEALYLVCGEEG
- MHC: H2 class II
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, IHC-Fr
- PE-A*02:01/Human INS (AQWGPDPAAA) MHC Tetramer (MHC-LC905)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: AQWGPDPAAA
- Conjugate: PE
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- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GSLQPLALEGSLQKRG
- Conjugate: PE
- PE-H2-K1/Human INS (LYLVCGERG) MHC Tetramer (MHC-LC977)
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- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERG
- Conjugate: PE
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: IHC-P
- Mouse Anti-INS Recombinant Antibody (MOB-0058F) (MOB-0058F)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
- Mouse Anti-INS Recombinant Antibody (MOB-0059F) (MOB-0059F)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, IHC
- Recombinant Human Anti-INS Soluble TCR (FS17) (ZIP-Fos/ZIP-Jun) (VS-0622-YF157)
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- Species Reactivity: Human
- Epitope: GSLQPLALEGSLQKRG
- MHC: HLA-DR4
- Mouse Anti-INS Recombinant Antibody (clone BE3F9) (FAMAB-0356JF)
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- Species Reactivity: Bovine
- Type: Mouse IgG2a
- Application: ELISA, FuncS
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
- Anti-INS Recombinant Antibody (Clone 5ins16) (PABS-0026)
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- Derivation: Yeast cell surface display
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, FuncS
- Mouse Anti-INS Recombinant Antibody (clone CB5) (FAMAB-0354JF)
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- Species Reactivity: Bovine
- Type: Mouse IgG1
- Application: ELISA, FuncS
- Mouse Anti-INS Recombinant Antibody (clone CA4) (FAMAB-0355JF)
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- Species Reactivity: Bovine
- Type: Mouse IgG2b
- Application: ELISA, FuncS
- Mouse Anti-INS Recombinant Antibody (clone CG7C7) (FAMAB-0352JF)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, FuncS
- Mouse Anti-INS Recombinant Antibody (clone AE9D6) (FAMAB-0353JF)
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- Species Reactivity: Bovine
- Type: Mouse IgG1
- Application: ELISA, FuncS
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- Class: Class II
- Antigen: Proinsulin
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: Biotin
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- Class: Class II
- Antigen: Proinsulin
- Antigen Species: Human
- Peptide: GIVEQCCTSICSLYQ
- Conjugate: Biotin
- A*02:01/Human Ins B. 10 (HLVEALYLV) MHC Monomer (MHC-YF236)
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- Class: Class I
- Antigen: Ins B. 10
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: Biotin
- Human Anti-INS Recombinant Antibody (clone mAb48) (HPAB-1993-FY)
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- Species Reactivity: Human
- Type: Human IgG3, κ
- Application: ELISA
- Human Anti-INS Recombinant Antibody (clone mAb13) (HPAB-1995-FY)
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA
- Human Anti-INS Recombinant Antibody (clone mAb49) (HPAB-1994-FY)
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA
- Human Anti-INS Recombinant Antibody (clone mAb49); Fab Fragment (HPAB-1994-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab, κ
- Application: ELISA
- Human Anti-INS Recombinant Antibody (clone mAb13); Fab Fragment (HPAB-1995-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab, κ
- Application: ELISA
- Human Anti-INS Recombinant Antibody (clone mAb13); scFv Fragment (HPAB-1995-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-INS Recombinant Antibody (clone mAb48); Fab Fragment (HPAB-1993-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab, κ
- Application: ELISA
- Human Anti-INS Recombinant Antibody (clone mAb48); scFv Fragment (HPAB-1993-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone AE9D6); Fab Fragment (FAMAB-0353JF-F(E))
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- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA, FuncS
- Mouse Anti-INS Recombinant Antibody (clone AE9D6); scFv Fragment (FAMAB-0353JF-S(P))
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- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA, FuncS
- Mouse Anti-INS Recombinant Antibody (clone CG7C7); Fab Fragment (FAMAB-0352JF-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FuncS
- Mouse Anti-INS Recombinant Antibody (clone CG7C7); scFv Fragment (FAMAB-0352JF-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FuncS
- Mouse Anti-INS Recombinant Antibody (clone CA4); Fab Fragment (FAMAB-0355JF-F(E))
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- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA, FuncS
- Mouse Anti-INS Recombinant Antibody (clone CA4); scFv Fragment (FAMAB-0355JF-S(P))
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- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA, FuncS
- Mouse Anti-INS Recombinant Antibody (clone CB5); Fab Fragment (FAMAB-0354JF-F(E))
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- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA, FuncS
- Mouse Anti-INS Recombinant Antibody (clone CB5); scFv Fragment (FAMAB-0354JF-S(P))
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- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA, FuncS
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- Derivation: Yeast cell surface display
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, FuncS
- Recombinant Anti-human INS VHH Single Domain Antibody (NAB-1554-VHH)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ICC, ChiP, FA, ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-INS Recombinant Antibody (clone BE3F9); Fab Fragment (FAMAB-0356JF-F(E))
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- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA, FuncS
- Mouse Anti-INS Recombinant Antibody (clone BE3F9); scFv Fragment (FAMAB-0356JF-S(P))
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- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA, FuncS
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- Derivation: Yeast cell surface display
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, FuncS
- Anti-INS Immunohistochemistry Kit (VS-0525-XY3566)
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- Species Reactivity: Human
- Target: INS
- Application: IHC
- Anti-Mouse INS Immunohistochemistry Kit (VS-0525-XY3567)
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- Species Reactivity: Human, Mouse, Rat
- Target: INS
- Application: IHC
- Anti-Rat INS Immunohistochemistry Kit (VS-0525-XY3568)
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- Species Reactivity: Human, Rat, Porcine, Bovine, Rabbit
- Target: INS
- Application: IHC
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- Species Reactivity: Bovine
- Target: INS
- Type: Tandem scFv
- Application: ELISA
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For Research Use Only. Not For Clinical Use.
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.