Human Anti-ADGRE5 Recombinant Antibody (clone A8)
CAT#: VS-0326-FY7
This is a high-affinity, human synthetic monoclonal antibody specifically engineered to target the highly conserved GAIN domain of Adhesion GPCR CD97 (ADGRE5).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13707/if_selected.jpg
Normal Tissue
Figure 2 High expression in spleen
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13707/30814_B_8_4_val_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13707/30814_B_8_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Enterocytes Staining: Low Intensity: Moderate Quantity: <25% Enterocytes - Goblet cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Mucosal lymphoid cells Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13707/30524_A_9_3.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13707/30524_A_6_6.jpg
Normal Tissue
Figure 6 Bone marrow
Hematopoietic cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13707/30814_B_4_4.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13707/30524_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000123146-ADGRE5
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Specifications
- Immunogen
- Purified Extracellular Regions (ECR) of CD97
- Host Species
- Human
- Type
- Human IgG1
- Antibody Isotype
- IgG1
- Specificity
- Human CD97 (No binding to homolog EMR2)
- Species Reactivity
- Human
- Clone
- A8
- Applications
- Cytotoxicity
- Related Disease
- Vibratory Urticaria, Thyroid Cancer
Product Property
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Adhesion G Protein-Coupled Receptor E5; Leukocyte Antigen CD97; CD97 Antigen; Seven-Transmembrane, Heterodimeric Receptor Associated With Inflammation; Seven Transmembrane Helix Receptor; Seven-Span Transmembrane Protein; CD97 Molecule; TM7LN1; CD97
- Gene ID
- 976
- UniProt ID
- P48960
- Long Name
- Adhesion G Protein-Coupled Receptor E5
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.
- Protein Refseq
- NP_510966.1; NP_001775.2; NP_001020331.1
- Function
- Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "ADGRE5"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2433z | Mouse Anti-ADGRE5 Recombinant Antibody (clone 31A9) | WB, ELISA | Mouse IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-010CQ | Mouse Anti-ADGRE5 Recombinant Antibody (NEUT-010CQ) | Neut | Mouse IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-011CQ | Mouse Anti-ADGRE5 Recombinant Antibody (clone CBL269) | Neut, WB, FC, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-012CQ | Mouse Anti-ADGRE5 Recombinant Antibody (clone CBL373) | Neut, FC, CyTOF, WB | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-013CQ | Mouse Anti-ADGRE5 Recombinant Antibody (clone CBL767) | ELISA(Cap), Neut | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-014CQ | Rat Anti-ADGRE5 Recombinant Antibody (clone CBL379) | Block, CyTOF, FC | Rat IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0594 | Hi-Affi™ Rabbit Anti-ADGRE5 Recombinant Antibody (clone DS594AB) | WB, IHC, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0600J | Rabbit Anti-ADGRE5 Recombinant Antibody (clone 3A7) | ELISA, IHC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY3253 | Rabbit Anti-ADGRE5 Recombinant Antibody (clone R05-4Z1) | WB, IHC-P, ICC, IF, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC372 | AbPlus™ Anti-Adgre5 Magnetic Beads (VS-0724-YC372) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC456 | AbPlus™ Anti-ADGRE5 Magnetic Beads (VS-0724-YC456) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY170 | Anti-ADGRE5 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY171 | Anti-Rat ADGRE5 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY172 | Anti-Mouse ADGRE5 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0326-YC478 | Mouse Anti-ADGRE5 Recombinant Antibody (AD478) | ELISA, IHC, FC | Mouse IgG2a |
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