Afuco™ Anti-AOC3 ADCC Recombinant Antibody (Timolumab), ADCC Enhanced (CAT#: AFC-TAB-455CQ)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to AOC3. Timolumab is a human monoclonal antibody that can be potentially used in the treatment of Psoriasis, Rheumatoid arthritis, Primary sclerosing cholangitis.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/980/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/980/if_selected.jpg
Figure 2 Lung
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/980/2500_A_1_4_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/980/2500_A_1_4_val_selected.jpg
Figure 3 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/980/2500_A_7_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/980/2500_A_7_3.jpg
Figure 4 Soft tissue
(Fibroblasts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25797/57908_B_2_8.jpg
(Fibroblasts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25797/57908_B_2_8.jpg
Figure 5 RNA cell line category: Cell line enriched (ASC diff)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131471-AOC3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131471-AOC3
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Specificity
- Human AOC3
- Species Reactivity
- Human
- Clone
- Timolumab
- Applications
- ELISA, IHC, FC, IP, IF, FuncS
- Conjugate
- Unconjugated
- Generic Name
- Timolumab
- Related Disease
- Psoriasis, Rheumatoid arthritis, Primary sclerosing cholangitis
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Amine Oxidase, Copper Containing 3; Semicarbazide-Sensitive Amine Oxidase; Vascular Adhesion Protein 1; Copper Amine Oxidase; EC 1.4.3.21; VAP-1; HPAO; SSAO; VAP1; Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1); Placenta Copper Monamine Oxidase; EC 1.4.3
- Gene ID
- 8639
- UniProt ID
- Q16853
Related Resources
Please refer to Timolumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Timolumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Timolumab"
Anti-Human AOC3 Recombinant Antibody (Timolumab)Recombinant monoclonal antibody to AOC3. Timolumab is a human monoclonal antibody that can be potentially used in the treatment of Psoriasis, Rheumatoid arthritis, Primary sclerosing cholangitis.
See other products for "AOC3"
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3906z | Mouse Anti-AOC3 Recombinant Antibody (clone 40D3) | WB, ELISA, FC, IHC, IP | Mouse IgG2a, κ |
| HPAB-1627LY | Mouse Anti-AOC3 Recombinant Antibody (clone 1G3) | ELISA | Mouse IgG |
| HPAB-1628LY | Mouse Anti-AOC3 Recombinant Antibody (clone 3F10) | ELISA | Mouse IgG |
| FAMAB-1004CQ | Mouse Anti-AOC3 Recombinant Antibody (clone 2D10) | IP, WB, ELISA, FC, IHC | Mouse IgG1 |
| FAMAB-1005CQ | Mouse Anti-AOC3 Recombinant Antibody (clone TK8-14) | IF, WB, FC | Mouse IgG2a |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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