Human Anti-ASTL Recombinant Antibody (clone SB2) (CAT#: HPAB-3129LY)
This product is an antibody that recognizes SAS1B. The antibody SB2 can be used for immunoassay techniques such as: ELISA, WB, IF.
Specific Inquiry
FC
Figure 1 SAS1B surface expression in pancreatic cancer cell lines correlated to anti-SAS1B ADC cell killing in vitro.
Median fluorescent intensity of cell surface SAS1B detected by live cell flow cytometry with SB2 monoclonal antibody (blue line) or unrelated control antibody (red line) on PDAC cell lines keratinocytes.
Knapp, K. A., Pires, E. S., Adair, S. J., Mandal, A., Mills, A. M., Olson, W. C., ... & Herr, J. C. (2018). Evaluation of SAS1B as a target for antibody-drug conjugate therapy in the treatment of pancreatic cancer. Oncotarget, 9(10), 8972.
IF
Figure 2 SAS1B localized to the cytoplasm and to the cell surface in pancreatic cancer cell lines.
Fixed and permeabilized indirect immunofluorescence (IIF) using anti-SAS1B mAb, SB2 showed SAS1B localized to the cytoplasm of pancreatic cancer cell line 608 compared to normal keratinocytes.
Knapp, K. A., Pires, E. S., Adair, S. J., Mandal, A., Mills, A. M., Olson, W. C., ... & Herr, J. C. (2018). Evaluation of SAS1B as a target for antibody-drug conjugate therapy in the treatment of pancreatic cancer. Oncotarget, 9(10), 8972.
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- Human IgG2b
- Specificity
- Human ASTL
- Species Reactivity
- Human
- Clone
- SB2
- Applications
- FC, IF
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Flow Cytometry and Immunofluorescence. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. should be carefully titrated in specific assays.
Target
- Alternative Names
- Astacin Like Metalloendopeptidase; Astacin-Like Metallo-Endopeptidase (M12 Family); Sperm Acrosomal SLLP1 Binding; Oocyte Astacin; Ovastacin; Astacin-Like Metalloendopeptidase (M12 Family); Astacin-Like Metalloendopeptidase
- Gene ID
- 431705
- UniProt ID
- Q6HA08
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone SB2"
See other products for "ASTL"
Select a product category from the dropdown menu below to view related products.
Please select product type
Immunotoxin Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L044S | anti-ASTL immunotoxin D-8 (Fab)-Sap | Cytotoxicity assay, Functional assay |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-3129LY. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: WB, IP, IF, FuncS, FC, Neut, ELISA
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, WB
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, SPR, Inhib, FuncS
-1-1.png)
Application: WB, ELISA, Neut, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, Vaccine, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
