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ASTL
Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (T-cells, Macrophages, Glandular and luminal cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (RT4)
Interaction
Interacts (via N-terminal domain) with SPACA3; the interaction occurs during fertilization.
Molecular function
Hydrolase, Metalloprotease, Protease
More Types Infomation
- Human Anti-ASTL Recombinant Antibody (clone SB4); scfv Fragment (HPAB-3130LY-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA, WB, IF
- Human Anti-ASTL Recombinant Antibody (clone SB2); scfv Fragment (HPAB-3129LY-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA, WB, IF
- Human Anti-ASTL Recombinant Antibody (clone SB1); scfv Fragment (HPAB-3128LY-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA, WB, IF
- Human Anti-ASTL Recombinant Antibody (clone SB5); Fab Fragment (HPAB-3131LY-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB, IF
- Human Anti-ASTL Recombinant Antibody (clone SB4); Fab Fragment (HPAB-3130LY-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB, IF
- Human Anti-ASTL Recombinant Antibody (clone SB2); Fab Fragment (HPAB-3129LY-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB, IF
- Human Anti-ASTL Recombinant Antibody (clone SB1); Fab Fragment (HPAB-3128LY-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB, IF
- Rabbit Anti-ASTL Recombinant Antibody (clone 31H1/31K1); Fab Fragment (HPAB-M0642-YC-F(E))
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- Species Reactivity: Human
- Type: Rabbit Fab
- Application: WB
- Rabbit Anti-ASTL Recombinant Antibody (clone 9H1/9K5); Fab Fragment (HPAB-M0641-YC-F(E))
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- Species Reactivity: Human
- Type: Rabbit Fab
- Application: WB
- Rabbit Anti-ASTL Recombinant Antibody (clone 7H1/7K3); Fab Fragment (HPAB-M0640-YC-F(E))
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- Species Reactivity: Human
- Type: Rabbit Fab
- Application: WB
- Rabbit Anti-ASTL Recombinant Antibody (clone 6H2/6K1); Fab Fragment (HPAB-M0639-YC-F(E))
-
- Species Reactivity: Human
- Type: Rabbit Fab
- Application: WB
- Rabbit Anti-ASTL Recombinant Antibody (clone 5H2/5K1); Fab Fragment (HPAB-M0638-YC-F(E))
-
- Species Reactivity: Human
- Type: Rabbit Fab
- Application: WB
- Rabbit Anti-ASTL Recombinant Antibody (clone 3H4/3K5); Fab Fragment (HPAB-M0637-YC-F(E))
-
- Species Reactivity: Human
- Type: Rabbit Fab
- Application: WB
- Rabbit Anti-ASTL Recombinant Antibody (clone 2H2/2K5); Fab Fragment (HPAB-M0636-YC-F(E))
-
- Species Reactivity: Human
- Type: Rabbit Fab
- Application: WB, FC
- Rabbit Anti-ASTL Recombinant Antibody (clone 1H3/1K3); Fab Fragment (HPAB-M0635-YC-F(E))
-
- Species Reactivity: Human
- Type: Rabbit Fab
- Application: WB, FC
- Rabbit Anti-ASTL Recombinant Antibody (clone 1H2/1K2); Fab Fragment (HPAB-M0634-YC-F(E))
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- Species Reactivity: Human
- Type: Rabbit Fab
- Application: WB, FC
- Mouse Anti-ASTL Recombinant Antibody (clone 6B1); Fab Fragment (HPAB-M0633-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, IF
- Mouse Anti-ASTL Recombinant Antibody (clone 3F2); Fab Fragment (HPAB-M0632-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, IF
- Mouse Anti-ASTL Recombinant Antibody (clone 6C1); Fab Fragment (HPAB-M0631-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, IP
- Mouse Anti-ASTL Recombinant Antibody (clone 7H2); Fab Fragment (HPAB-M0630-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, IP
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