Recombinant Anti-BMP2 (AA 282-299 x AA 369-383) Biparatopic Antibody, Tandem scFv (Clone 11F2 x Clone 8B3)
CAT#: VS-0525-YC23
The recombinant Anti-BMP2 (AA 282-299 x AA 369-383) biparatopic antibody, tandem scFv (Clone 11F2 x Clone 8B3), targets two specific epitopes within BMP2. This antibody uses a tandem scFv construction, where the 11F2 scFv binds a BMP2 epitope (QAKHKQRKRLKSSCKRH) and is fused to the N-terminus of the 8B3 scFv, which binds another BMP2 epitope (ISMLYLDENEKVVLK) tied to its type 2 receptor.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RT4
Immunofluorescent staining of human cell line RT4 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58610/1596_D8_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78457/1727_A2_1_selected.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (CACO-2, HeLa, hTERT-HME1, RT4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125845-BMP2
❮
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Specifications
- Host Animal 1
- Human
- Host Animal 2
- Human
- Specificity
- Human BMP2
- Species Reactivity
- Human
- Type
- Tandem scFv
- Valency
- 1 + 1
- Clone 1
- 11F2
- Clone 2
- 8B3
- Epitope 1
- A BMP2 epitope: QAKHKQRKRLKSSCKRH
- Epitope 2
- A BMP2 epitope: ISMLYLDENEKVVLK that binds a BMP2 type 2 receptor
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- Block, ELISA, FC, IHC, WB
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- Bone Morphogenetic Protein 2
Target
- Introduction
- This gene encodes a member of the transforming growth factor-beta (TGFB) superfamily. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which induces bone and cartilage formation.
- Alternative Names
- BDA2; BMP2A
- Gene ID
- 650
- UniProt ID
- P12643
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Related Signaling Pathways
TGF-β Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| HPAB-0169-YC | Human Anti-BMP2 Recombinant Antibody (clone 8B3) | ELISA, FC, IHC, WB, Block | Human IgG |
| HPAB-0170-YC | Human Anti-BMP2 Recombinant Antibody (clone 11F2) | ELISA, FC, IHC, WB, Block | Human IgG |
| MRO-1697-CN | Rabbit Anti-BMP2 Polyclonal Antibody (MRO-1697-CN) | WB, IF, IHC, FC | Rabbit IgG |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0169-YC-S(P) | Human Anti-BMP2 Recombinant Antibody (clone 8B3); scFv Fragment | ELISA, FC, IHC, WB | Human scFv |
| HPAB-0170-YC-S(P) | Human Anti-BMP2 Recombinant Antibody (clone 11F2); scFv Fragment | ELISA, FC, IHC, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0169-YC-F(E) | Human Anti-BMP2 Recombinant Antibody (clone 8B3); Fab Fragment | ELISA, FC, IHC, WB | Human Fab |
| HPAB-0170-YC-F(E) | Human Anti-BMP2 Recombinant Antibody (clone 11F2); Fab Fragment | ELISA, FC, IHC, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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