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BMP2

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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016]

Species Reactivity:
Zebrafish
Type:
IgG1
Application:
Neut, WB
Species Reactivity:
Human
Type:
Human IgG
Application:
ELISA, FC, IHC, WB
Species Reactivity:
Human
Type:
Human IgG
Application:
ELISA, FC, IHC, WB
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
WB, IF, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
WB, Neut, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
ELISA, WB, IF, FuncS
Species Reactivity:
Human
Application:
IHC-P, WB
Species Reactivity:
Human
Type:
IgG
Application:
ICC/IF
Species Reactivity:
Human
Type:
Human scFv
Application:
ELISA, FC, IHC, WB
Species Reactivity:
Human
Type:
Human scFv
Application:
ELISA, FC, IHC, WB
Species Reactivity:
Human
Type:
Human Fab
Application:
ELISA, FC, IHC, WB
Species Reactivity:
Human
Type:
Human Fab
Application:
ELISA, FC, IHC, WB
Species Reactivity:
Human, Mouse, Rat
Type:
Rabbit IgG
Application:
WB, IF, IHC, FC
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