Mouse Anti-CD200R1 Recombinant Antibody (clone OX131) (CAT#: FAMAB-1740CQ)

This product is a recombinant mouse antibody that recognizes CD200R1. The antibody was purified by affinity chromatography. It can be used in FC.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA

Figure 1 The effects of CD200R and CD200 mAb on T cell activation.

Figure 1 The effects of CD200R and CD200 mAb on T cell activation.

Effect of different mAb on IL-2 release. Either CHO-IEk cells (left panel) or CHO-IEk CD200 cells (right panel) were used together with CD200R(1) expressing T cells and IL-2 concentrations were measured. Effects of mAb were statistically compared with no mAb applied condition (representative of more than seven experiments).

Akkaya, M., Aknin, M. L., Akkaya, B., & Barclay, A. N. (2013). Dissection of agonistic and blocking effects of CD200 receptor antibodies. PLoS One, 8(5), e63325.

Figure 2 The effects of CD200R and CD200 mAb on T cell activation.

Figure 2 The effects of CD200R and CD200 mAb on T cell activation.

Akkaya, M., Aknin, M. L., Akkaya, B., & Barclay, A. N. (2013). Dissection of agonistic and blocking effects of CD200 receptor antibodies. PLoS One, 8(5), e63325.

Figure 3 The effects of CD200R and CD200 mAb on T cell activation.

Figure 3 The effects of CD200R and CD200 mAb on T cell activation.

10 µg/ml of OX110, OX131, OX132 (control) or no mAb were immobilized onto plates together with 0.5 µg/ml of CD3 mAb. CD200R(1) expressing 2B4 Reay cells were incubated overnight and IL-2 release in each condition was assayed. IL-2 levels obtained by each mAb stimulated condition were statistically compared with no mAb stimulated control. (representative of three experiments).

Akkaya, M., Aknin, M. L., Akkaya, B., & Barclay, A. N. (2013). Dissection of agonistic and blocking effects of CD200 receptor antibodies. PLoS One, 8(5), e63325.


Specifications

  • Immunogen
  • Recombinant protein consisting of the extracellular regions of CD200R and CD200RLc together with rCD4d3+4
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • Mouse CD200R
  • Species Reactivity
  • Mouse
  • Clone
  • OX131
  • Applications
  • FC

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • CD200 Receptor 1; Cell Surface Glycoprotein OX2 Receptor 1; CD200 Cell Surface Glycoprotein Receptor; MOX2 Receptor; CD200R; MOX2R;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone OX131"

See other products for "CD200R1"

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4030 Hi-Affi™ Rabbit Anti-CD200R1 Recombinant Antibody (clone SI95DS) ELISA Rabbit IgG

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for FAMAB-1740CQ. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare