Mouse Anti-CD200R1 Recombinant Antibody (clone OX131) (CAT#: FAMAB-1740CQ)
This product is a recombinant mouse antibody that recognizes CD200R1. The antibody was purified by affinity chromatography. It can be used in FC.
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Figure 1 The effects of CD200R and CD200 mAb on T cell activation.
Effect of different mAb on IL-2 release. Either CHO-IEk cells (left panel) or CHO-IEk CD200 cells (right panel) were used together with CD200R(1) expressing T cells and IL-2 concentrations were measured. Effects of mAb were statistically compared with no mAb applied condition (representative of more than seven experiments).
Akkaya, M., Aknin, M. L., Akkaya, B., & Barclay, A. N. (2013). Dissection of agonistic and blocking effects of CD200 receptor antibodies. PLoS One, 8(5), e63325.
Figure 2 The effects of CD200R and CD200 mAb on T cell activation.
Akkaya, M., Aknin, M. L., Akkaya, B., & Barclay, A. N. (2013). Dissection of agonistic and blocking effects of CD200 receptor antibodies. PLoS One, 8(5), e63325.
Figure 3 The effects of CD200R and CD200 mAb on T cell activation.
10 µg/ml of OX110, OX131, OX132 (control) or no mAb were immobilized onto plates together with 0.5 µg/ml of CD3 mAb. CD200R(1) expressing 2B4 Reay cells were incubated overnight and IL-2 release in each condition was assayed. IL-2 levels obtained by each mAb stimulated condition were statistically compared with no mAb stimulated control. (representative of three experiments).
Akkaya, M., Aknin, M. L., Akkaya, B., & Barclay, A. N. (2013). Dissection of agonistic and blocking effects of CD200 receptor antibodies. PLoS One, 8(5), e63325.
Specifications
- Immunogen
- Recombinant protein consisting of the extracellular regions of CD200R and CD200RLc together with rCD4d3+4
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Mouse CD200R
- Species Reactivity
- Mouse
- Clone
- OX131
- Applications
- FC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD200 Receptor 1; Cell Surface Glycoprotein OX2 Receptor 1; CD200 Cell Surface Glycoprotein Receptor; MOX2 Receptor; CD200R; MOX2R;
- Gene ID
- 57781
- UniProt ID
- Q9ES57
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3343z | Mouse Anti-CD200R1 Recombinant Antibody (clone 34D9) | ELISA, WB, FC | Mouse IgG1, κ |
| MOB-2282MZ | Mouse Anti-CD200R1 Recombinant Antibody (clone NSD PY203) | FC | Mouse IgG1 |
| HPAB-0038-DJB | Human Anti-CD200R1 Recombinant Antibody (HPAB-0038-DJB) | ELISA, FuncS | Human IgG2 |
| FN-246CQ | Mouse Anti-CD200R1 Recombinant Antibody (clone OX108) | FC, FuncS, IF | Mouse IgG1, κ |
| FAMAB-1617CQ | Mouse Anti-CD200R1 Recombinant Antibody (clone OX102) | IP, WB, Block, FC, IHC-Fr | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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