AbPlus™ Anti-CD46 Magnetic Beads (VS-0424-XY54)
CAT#: VS-0424-XY54
The AbPlus Anti-CD46 Magnetic Beads (VS-0424-XY54) is an innovative affinity resin which is bound with anti-CD46 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of CD46 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/if_selected.jpg
Subcellular Location
Figure 2 IHC staining of human placenta
Immunohistochemical staining of human placenta shows strong membranous positivity in trophoblastic cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/ihc_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/211_E5_1_blue_red_green.jpg
Subcellular Location
Figure 4 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/209_E5_1_blue_red_green.jpg
Normal Tissue
Figure 5 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16903/38899_A_9_3.jpg
RNA Expression
Figure 6 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117335-CD46
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-CD46 specific antibody
- Target
- CD46
- Target Species
- Human
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
- Alternative Names
- CD46 Molecule, Complement Regulatory Protein; Membrane Cofactor Protein (CD46, Trophoblast-Lymphocyte Cross-Reactive Antigen); Antigen Identified By Monoclonal Antibody TRA-2-10; CD46 Antigen, Complement Regulatory Protein; Trophoblast Leukocyte Common Antigen; MIC10; MCP; TLX; Trophoblast-Lymphocyte Cross-Reactive Antigen; Complement Membrane Cofactor Protein; Trophoblast Leucocyte Common Antigen; Measles Virus Receptor; CD46 Antigen; TRA2.10; AHUS2
- Gene ID
- 4179
- UniProt ID
- P15529
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CD46"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0288CL | Human Anti-CD46 Recombinant Antibody (TAB-0288CL) | RIA, ELISA, FC | Human IgG1 |
| TAB-0289CL | Human Anti-CD46 Recombinant Antibody (TAB-0289CL) | RIA, ELISA, FC | Human IgG1 |
| TAB-0290CL | Human Anti-CD46 Recombinant Antibody (TAB-0290CL) | RIA, ELISA, FC | Human IgG1 |
| TAB-0291CL | Human Anti-CD46 Recombinant Antibody (TAB-0291CL) | RIA, ELISA, FC | Human IgG1 |
| TAB-0292CL | Human Anti-CD46 Recombinant Antibody (TAB-0292CL) | RIA, ELISA, FC | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-268LC | Mouse Anti-CD46 Recombinant Antibody (TAB-268LC) | Cyt, FuncS | Mouse IgG |
| TAB-269LC | Mouse Anti-CD46 Recombinant Antibody (TAB-269LC) | Cyt, FuncS | Mouse IgG |
| TAB-268LC-F(E) | Mouse Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-268LC-F(E)) | FC, ELISA | Mouse Fab |
| TAB-269LC-F(E) | Mouse Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-269LC-F(E)) | FC, ELISA | Mouse Fab |
| TAB-272LC-F(E) | Anti-Human CD46 Recombinant Antibody Fab Fragment (mPA7) | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-270LC | Human Anti-CD46 Recombinant Antibody (TAB-270LC) | Cyt, FuncS | Humanized IgG1, κ |
| TAB-271LC | Human Anti-CD46 Recombinant Antibody (TAB-271LC) | Cyt, FuncS | Humanized IgG1, κ |
| TAB-270LC-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-270LC-S(P)) | FC, ELISA | Humanized scFv |
| TAB-270LC-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-270LC-F(E)) | FC, ELISA | Humanized Fab |
| TAB-271LC-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-271LC-F(E)) | FC, ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-385CQ | Mouse Anti-CD46 Recombinant Antibody (NEUT-385CQ) | FC, Block, IF, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0564 | Hi-Affi™ Rabbit Anti-CD46 Recombinant Antibody (clone DS564AB) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0524-CN-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0524-CN-S(P)) | WB, ELISA, FC, IHC, IP | Human scFv |
| HPAB-0525-CN-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0525-CN-S(P)) | WB, ELISA, FC, IHC, IP | Human scFv |
| HPAB-0366-YC-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0366-YC-S(P)) | ELISA, FC | Humanized scFv |
| HPAB-0368-YC-S(P) | Mouse Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0368-YC-S(P)) | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0524-CN-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (HPAB-0524-CN-F(E)) | WB, ELISA, FC, IHC, IP | Human Fab |
| HPAB-0525-CN-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (HPAB-0525-CN-F(E)) | WB, ELISA, FC, IHC, IP | Human Fab |
| HPAB-0367-YC-F(E) | Mouse Anti-CD46 Recombinant Antibody (clone SC1.N122); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0368-YC-F(E) | Mouse Anti-CD46 Recombinant Antibody; Fab Fragment (HPAB-0368-YC-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0022-FY | Mouse Anti-CD46 Recombinant Antibody (clone M177) | FC, FuncS, IA, IP, WB | Mouse IgG1 |
| VS-0723-WK258 | Rabbit Anti-CD46 Recombinant Antibody (VS-0723-WK258) | ELISA, FC | Rabbit IgG |
| VS7-HM600 | Mouse Anti-CD46 Recombinant Antibody (clone 1A5A5) | IHC, FCM | Mouse IgG1 |
| VS7-HM601 | Mouse Anti-CD46 Recombinant Antibody (clone 5A8C11) | WB, ICC, FCM | Mouse IgG1 |
| VS13-YC166 | Rabbit Anti-CD46 Recombinant Antibody (VS13-YC166) | WB, ICC, IF, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC422 | AbPlus™ Anti-CD46 Magnetic Beads (VS-0724-YC422) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY113 | Mouse Anti-CD46 (clone mPA7) scFv-Fc Chimera | Inhib, WB | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY367 | Anti-CD46 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1189 | Anti-Rat CD46 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1190 | Anti-Mouse CD46 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1188 | Anti-Human CD46 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC188 | Recombinant Anti-CD46 Vesicular Antibody, EV Displayed (VS-0425-YC188) | ELISA, FC, Cell-uptake |
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