Recombinant Anti-CD46 Vesicular Antibody, EV Displayed (VS-0425-YC188) (CAT#: VS-0425-YC188)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• CD46

• Host Animal
• Human

• Antibody Isotype
• IgG1

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• CD46 molecule

• Biological Process
• Complement pathway, Fertilization, Host-virus interaction, Immunity, Innate immunity

• Molecular Function
• Host cell receptor for virus entry, Receptor

• Cellular Localization
• Plasma membrane

• Introduction
• CD46 (CD46 Molecule) is a Protein Coding gene. Diseases associated with CD46 include Hemolytic Uremic Syndrome, Atypical 2 and Measles. Among its related pathways are Creation of C4 and C2 activators and Complement and coagulation cascades. Gene Ontology (GO) annotations related to this gene include receptor activity and enzyme inhibitor activity. An important paralog of this gene is C4BPA.

• Alternative Names
• MCP, MGC26544, MIC10, TLX, TRA2.10

• Gene ID
• 4179

• UniProt ID
• P15529

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