Anti-Human CD46 Recombinant Antibody (mPA7) (CAT#: TAB-272LC)
Recombinant monoclonal antibody to CD46. mPA7 is a mouse monoclonal antibody that can be potentially used in the treatment of cancers.
Specific Inquiry
Inhib
Figure 1 is a graph that shows inhibition of LnCaP prostatic carcinoma cell growth in a monolayer by mPA7.
WB
Figure 2 is a graph which shows the epitope that mPA7 binds is disulfide bond dependent.
FuncS
Figure 3 is a graph shows the effect of mPA7 and Mab-ZAP (an anti-IgG conjugate to saporin) on the growth of human prostate tumor cells LNCaP.
Specifications
- Immunogen
- hPED
- Host Species
- Mouse
- Specificity
- Human
- Clone
- mPA7
- Applications
- FuncS, Inhib, WB
- Related Disease
- Cancers
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay, Inhibition, Western Blot.
Target
- Alternative Names
- The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
- Gene ID
- 4179
- UniProt ID
- P15529
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone mPA7"
See other products for "CD46"
Select a product category from the dropdown menu below to view related products.
Please select product type
Human Antibody Products
Mouse Antibody Products
Humanized Antibody Products
Blocking Antibody Products
Rabbit Monoclonal Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
Antibody Magnetic Beads
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0288CL-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-0288CL-F(E)) | RIA, ELISA, FC | Human Fab |
| TAB-0289CL-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-0289CL-F(E)) | RIA, ELISA, FC | Human Fab |
| TAB-0290CL-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-0290CL-F(E)) | RIA, ELISA, FC | Human Fab |
| TAB-0291CL-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-0291CL-F(E)) | RIA, ELISA, FC | Human Fab |
| TAB-0292CL-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-0292CL-F(E)) | RIA, ELISA, FC | Human Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAB-272LC. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: WB, ELISA, IP, FC, FuncS, Neut, IF
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: WB, IF, FuncS
-1.png)
Application: WB, ELISA
Application: ELISA, IHC, FC, WB, IF, IA
Application: ELISA, WB, FC, IHC, IP
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
