Anti-Human CD46 Recombinant Antibody (mPA7) (CAT#: TAB-272LC)
Recombinant monoclonal antibody to CD46. mPA7 is a mouse monoclonal antibody that can be potentially used in the treatment of cancers.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Inhib
Figure 1 is a graph that shows inhibition of LnCaP prostatic carcinoma cell growth in a monolayer by mPA7.
WB
Figure 2 is a graph which shows the epitope that mPA7 binds is disulfide bond dependent.
FuncS
Figure 3 is a graph shows the effect of mPA7 and Mab-ZAP (an anti-IgG conjugate to saporin) on the growth of human prostate tumor cells LNCaP.
Specifications
- Immunogen
- hPED
- Host Species
- Mouse
- Specificity
- Human
- Clone
- mPA7
- Applications
- FuncS, Inhib, WB
- Related Disease
- Cancers
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay, Inhibition, Western Blot.
Target
- Alternative Names
- The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
- Gene ID
- 4179
- UniProt ID
- P15529
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibodies
Mouse Antibodies
Humanized Antibodies
Blocking Antibodies
Rabbit Monoclonal Antibodies
ScFv Antibodies
Fab Antibodies
IgG Antibodies
Antibody Magnetic Beads
ScFv-Fc Chimeras
IHC Kits & Antibodies
Extracellular Vesicle Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0288CL | Human Anti-CD46 Recombinant Antibody (TAB-0288CL) | RIA, ELISA, FC | Human IgG1 |
| TAB-0289CL | Human Anti-CD46 Recombinant Antibody (TAB-0289CL) | RIA, ELISA, FC | Human IgG1 |
| TAB-0290CL | Human Anti-CD46 Recombinant Antibody (TAB-0290CL) | RIA, ELISA, FC | Human IgG1 |
| TAB-0291CL | Human Anti-CD46 Recombinant Antibody (TAB-0291CL) | RIA, ELISA, FC | Human IgG1 |
| TAB-0292CL | Human Anti-CD46 Recombinant Antibody (TAB-0292CL) | RIA, ELISA, FC | Human IgG1 |
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For Research Use Only. Not For Clinical Use.
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