AbPlus™ Anti-CD46 Magnetic Beads (VS-0724-YC422)
CAT#: VS-0724-YC422
The AbPlus Anti-CD46 Magnetic Beads (VS-0724-YC422) is an innovative affinity resin which is bound with anti-CD46 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of CD46 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/if_selected.jpg
Subcellular Location
Figure 2 IHC staining of human placenta
Immunohistochemical staining of human placenta shows strong membranous positivity in trophoblastic cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/ihc_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/211_E5_1_blue_red_green.jpg
Subcellular Location
Figure 4 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/209_E5_1_blue_red_green.jpg
Normal Tissue
Figure 5 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16903/38899_A_9_3.jpg
RNA Expression
Figure 6 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117335-CD46
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-CD46 specific antibody
- Target
- CD46
- Immunogen
- Recombinant human CD46, aa 1-328.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- CD46 (CD46 Molecule) is a Protein Coding gene. Diseases associated with CD46 include Hemolytic Uremic Syndrome, Atypical 2 and Measles. Among its related pathways are Creation of C4 and C2 activators and Complement and coagulation cascades. Gene Ontology (GO) annotations related to this gene include receptor activity and enzyme inhibitor activity. An important paralog of this gene is C4BPA.
- Alternative Names
- CD46 Molecule; Membrane Cofactor Protein (CD46, Trophoblast-Lymphocyte Cross-Reactive Antigen); Antigen Identified By Monoclonal Antibody TRA-2-10; CD46 Molecule, Complement Regulatory Protein; CD46 Antigen, Complement Regulatory Protein; Trophoblast Leukocyte Common Antigen; MIC10; MCP; TLX;
- Gene ID
- 4179
- UniProt ID
- P15529
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0288CL-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-0288CL-S(P)) | RIA, ELISA, FC | Human scFv |
| TAB-0289CL-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-0289CL-S(P)) | RIA, ELISA, FC | Human scFv |
| TAB-0290CL-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-0290CL-S(P)) | RIA, ELISA, FC | Human scFv |
| TAB-0291CL-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-0291CL-S(P)) | RIA, ELISA, FC | Human scFv |
| TAB-0292CL-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-0292CL-S(P)) | RIA, ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-270LC | Human Anti-CD46 Recombinant Antibody (TAB-270LC) | Cyt, FuncS | Humanized IgG1, κ |
| TAB-270LC-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-270LC-S(P)) | FC, ELISA | Humanized scFv |
| TAB-271LC-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-271LC-S(P)) | FC, ELISA | Humanized scFv |
| TAB-270LC-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-270LC-F(E)) | FC, ELISA | Humanized Fab |
| TAB-271LC-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-271LC-F(E)) | FC, ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-268LC-S(P) | Mouse Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-268LC-S(P)) | FC, ELISA | Mouse scFv |
| TAB-269LC-S(P) | Mouse Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-269LC-S(P)) | FC, ELISA | Mouse scFv |
| TAB-268LC-F(E) | Mouse Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-268LC-F(E)) | FC, ELISA | Mouse Fab |
| TAB-269LC-F(E) | Mouse Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-269LC-F(E)) | FC, ELISA | Mouse Fab |
| TAB-272LC-F(E) | Anti-Human CD46 Recombinant Antibody Fab Fragment (mPA7) | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0504CT | Mouse Anti-CD46 Recombinant Antibody (clone NFN-369) | FC, IP, WB | Mouse IgG1 |
| MOR-0022-FY | Mouse Anti-CD46 Recombinant Antibody (clone M177) | FC, FuncS, IA, IP, WB | Mouse IgG1 |
| ZG-0134U | Rabbit Anti-CD46 Recombinant Antibody (clone 7D12) | ELISA, WB, IHC | Rabbit IgG |
| VS-0723-WK258 | Rabbit Anti-CD46 Recombinant Antibody (VS-0723-WK258) | ELISA, FC | Rabbit IgG |
| VS13-YC166 | Rabbit Anti-CD46 Recombinant Antibody (VS13-YC166) | WB, ICC, IF, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-385CQ | Mouse Anti-CD46 Recombinant Antibody (NEUT-385CQ) | FC, Block, IF, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0564 | Hi-Affi™ Rabbit Anti-CD46 Recombinant Antibody (clone DS564AB) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0524-CN-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0524-CN-S(P)) | WB, ELISA, FC, IHC, IP | Human scFv |
| HPAB-0525-CN-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0525-CN-S(P)) | WB, ELISA, FC, IHC, IP | Human scFv |
| HPAB-0366-YC-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0366-YC-S(P)) | ELISA, FC | Humanized scFv |
| HPAB-0368-YC-S(P) | Mouse Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0368-YC-S(P)) | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0524-CN-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (HPAB-0524-CN-F(E)) | WB, ELISA, FC, IHC, IP | Human Fab |
| HPAB-0525-CN-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (HPAB-0525-CN-F(E)) | WB, ELISA, FC, IHC, IP | Human Fab |
| HPAB-0367-YC-F(E) | Mouse Anti-CD46 Recombinant Antibody (clone SC1.N122); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0368-YC-F(E) | Mouse Anti-CD46 Recombinant Antibody; Fab Fragment (HPAB-0368-YC-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY54 | AbPlus™ Anti-CD46 Magnetic Beads (VS-0424-XY54) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY113 | Mouse Anti-CD46 (clone mPA7) scFv-Fc Chimera | Inhib, WB | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY367 | Anti-CD46 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1189 | Anti-Rat CD46 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1190 | Anti-Mouse CD46 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1188 | Anti-Human CD46 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC188 | Recombinant Anti-CD46 Vesicular Antibody, EV Displayed (VS-0425-YC188) | ELISA, FC, Cell-uptake |
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