AbPlus™ Anti-CD46 Magnetic Beads (VS-0724-YC422) (CAT#: VS-0724-YC422)
The AbPlus Anti-CD46 Magnetic Beads (VS-0724-YC422) is an innovative affinity resin which is bound with anti-CD46 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of CD46 protein under native and denaturing conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/if_selected.jpg

Figure 2 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong membranous positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/ihc_selected.jpg
(Immunohistochemical staining of human placenta shows strong membranous positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/ihc_selected.jpg

Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/211_E5_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/211_E5_1_blue_red_green.jpg

Figure 4 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/209_E5_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/209_E5_1_blue_red_green.jpg

Figure 5 Colon
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16903/38899_A_9_3.jpg
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16903/38899_A_9_3.jpg

Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117335-CD46
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117335-CD46
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-CD46 specific antibody
- Target
- CD46
- Immunogen
- Recombinant human CD46, aa 1-328.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- CD46 (CD46 Molecule) is a Protein Coding gene. Diseases associated with CD46 include Hemolytic Uremic Syndrome, Atypical 2 and Measles. Among its related pathways are Creation of C4 and C2 activators and Complement and coagulation cascades. Gene Ontology (GO) annotations related to this gene include receptor activity and enzyme inhibitor activity. An important paralog of this gene is C4BPA.
- Alternative Names
- CD46 Molecule; Membrane Cofactor Protein (CD46, Trophoblast-Lymphocyte Cross-Reactive Antigen); Antigen Identified By Monoclonal Antibody TRA-2-10; CD46 Molecule, Complement Regulatory Protein; CD46 Antigen, Complement Regulatory Protein; Trophoblast Leukocyte Common Antigen; MIC10; MCP; TLX;
- Gene ID
- 4179
- UniProt ID
- P15529
Downloads
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IgG Antibodies
Human Antibodies
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ScFv Antibodies
Fab Antibodies
Antibody Magnetic Beads
ScFv-Fc Chimeras
IHC Kits & Antibodies
Extracellular Vesicle Antibodies
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1132z | Mouse Anti-CD46 Recombinant Antibody (clone 12A2) | WB, ELISA, FC, IF, IHC, IP, FuncS | Mouse IgG1, κ |
MOB-0504CT | Mouse Anti-CD46 Recombinant Antibody (clone NFN-369) | FC, IP, WB | Mouse IgG1 |
MOR-0022-FY | Mouse Anti-CD46 Recombinant Antibody (clone M177) | FC, FuncS, IA, IP, WB | Mouse IgG1 |
VS7-HM600 | Mouse Anti-CD46 Recombinant Antibody (clone 1A5A5) | IHC, FCM | Mouse IgG1 |
VS7-HM601 | Mouse Anti-CD46 Recombinant Antibody (clone 5A8C11) | WB, ICC, FCM | Mouse IgG1 |
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