Mouse Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-269LC-S(P))

Name: Mouse Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-269LC-S(P))
SKU: TAB-269LC-S(P)
Rating: 5 (1 reviews)

CAT#: TAB-269LC-S(P)

This product is a recombinant mouse antibody scFv Fragment that recognizes CD46 (cluster of differentiation 46). The antibody was purified by affinity chromatography. It can be used for FC, ELISA and other applications.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/if_selected.jpg

Subcellular Location Figure 2 IHC staining of human placenta

Immunohistochemical staining of human placenta shows strong membranous positivity in trophoblastic cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/ihc_selected.jpg

Subcellular Location Figure 3 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/211_E5_1_blue_red_green.jpg

Subcellular Location Figure 4 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/209_E5_1_blue_red_green.jpg

Normal Tissue Figure 5 Colon

Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16903/38899_A_9_3.jpg

RNA Expression Figure 6 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117335-CD46

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Specifications

Immunogen
Synthetic CD46 peptide

Host Species
Mouse

Type
Mouse scFv

Specificity
Human

Species Reactivity
Human

Applications
FC, ELISA

Related Disease
Hyperproliferative disorder

Product Property

Purity
>95% as determined by SDS-PAGE

Buffer
PBS

Preservative
No preservatives

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene ID
4179

UniProt ID
P15529

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-269LC-S(P).pdf

MSDS

MSDS - TAB-269LC-S(P).pdf

COA

Certificate of Analysis Lookup

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TAB-269LC-F(E)	Mouse Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-269LC-F(E))	FC, ELISA	Mouse Fab

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TAB-270LC-S(P)	Human Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-270LC-S(P))	FC, ELISA	Humanized scFv
TAB-270LC-F(E)	Human Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-270LC-F(E))	FC, ELISA	Humanized Fab
TAB-271LC-F(E)	Human Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-271LC-F(E))	FC, ELISA	Humanized Fab

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HPAB-0524-CN	Human Anti-CD46 Recombinant Antibody (HPAB-0524-CN)	WB, ELISA, FC, IHC, IP	Human IgG1
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CAT	Product Name	Application	Type
HPAB-0524-CN-S(P)	Human Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0524-CN-S(P))	WB, ELISA, FC, IHC, IP	Human scFv
HPAB-0525-CN-S(P)	Human Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0525-CN-S(P))	WB, ELISA, FC, IHC, IP	Human scFv
HPAB-0366-YC-S(P)	Human Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0366-YC-S(P))	ELISA, FC	Humanized scFv
HPAB-0368-YC-S(P)	Mouse Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0368-YC-S(P))	ELISA, FC	Mouse scFv

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HPAB-0524-CN-F(E)	Human Anti-CD46 Recombinant Antibody; Fab Fragment (HPAB-0524-CN-F(E))	WB, ELISA, FC, IHC, IP	Human Fab
HPAB-0525-CN-F(E)	Human Anti-CD46 Recombinant Antibody; Fab Fragment (HPAB-0525-CN-F(E))	WB, ELISA, FC, IHC, IP	Human Fab
HPAB-0367-YC-F(E)	Mouse Anti-CD46 Recombinant Antibody (clone SC1.N122); Fab Fragment	ELISA, FC	Mouse Fab
HPAB-0368-YC-F(E)	Mouse Anti-CD46 Recombinant Antibody; Fab Fragment (HPAB-0368-YC-F(E))	ELISA, FC	Mouse Fab

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