CytoStream™ Mouse Anti-CD47 Recombinant Antibody (clone CC2C6)

Name: CytoStream™ Mouse Anti-CD47 Recombinant Antibody (clone CC2C6)
SKU: VS-0225-XY56
Rating: 5 (1 reviews)

CAT#: VS-0225-XY56

Targeting the human CD47 protein, this antibody excels in flow cytometry applications, offering precise detection of this key immune checkpoint molecule. Known for its role in regulating macrophage activity and immune evasion, CD47 is a critical target in immunotherapy research. The antibody provides reliable and consistent results, enabling in-depth analysis of immune interactions and offering valuable insights into the dynamics of immune responses in human models.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & vesicles.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16055/204_F3_1_selected.jpg

Subcellular Location Figure 2 IHC staining of human urinary bladder

Immunohistochemical staining of human urinary bladder shows strong cytoplasmic and membranous positivity in urothelial cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/ihc_selected.jpg

Subcellular Location Figure 3 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & vesicles.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16055/205_F3_1_blue_red_green.jpg

Normal Tissue Figure 4 Cerebral cortex

Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_B_8_5.jpg

Normal Tissue Figure 5 Colon

Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_A_8_3.jpg

Normal Tissue Figure 6 Testis

Elongated or late spermatids
Staining: Medium
Intensity: Moderate
Quantity:>75%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_A_4_6.jpg

Normal Tissue Figure 7 Prostate

Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_A_2_5.jpg

RNA Expression Figure 8 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196776-CD47

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Specifications

Host Species
Mouse

Type
Mouse IgG1

Specificity
CD47

Species Reactivity
Human

Clone
CC2C6

Applications
FC

Product Property

Purification
Protein A purified

Purity
>95%, determined by SDS-PAGE

Format
Liquid

Buffer
PBS

Preservative
Sodium azide

Storage
Store at 4°C for short-term storage and at -20°C for long-term storage. Avoid repeated freeze-thaw cycles.

Target

Alternative Names
CD47; IAP; integrin associated protein; MER6; OA3; Rh-related antigen

Gene ID
961

UniProt ID
Q08722

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS-0225-XY56.pdf

MSDS

MSDS - VS-0225-XY56.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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