Recombinant Anti-CD47 Vesicular Antibody, EV Displayed (VS-0425-YC635)
CAT#: VS-0425-YC635
The Recombinant Anti-CD47 Vesicular Antibody, EV Displayed (VS-0425-YC635) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD47-expressed cells or tissues. CD47 is a molecule implicated in diseases like hereditary spherocytosis, participating in pathways like the immune response to elevated Ca2+.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16055/204_F3_1_selected.jpg
Subcellular Location
Figure 2 IHC staining of human urinary bladder
Immunohistochemical staining of human urinary bladder shows strong cytoplasmic and membranous positivity in urothelial cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/ihc_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16055/205_F3_1_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_B_8_5.jpg
Normal Tissue
Figure 5 Colon
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_A_8_3.jpg
Normal Tissue
Figure 6 Testis
Elongated or late spermatids
Staining: Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_A_4_6.jpg
Normal Tissue
Figure 7 Prostate
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44659/124851_A_2_5.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196776-CD47
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD47
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD47 molecule
- Biological Process
- Angiogenesis, Apoptosis, Cell adhesion, Inflammatory response
- Cellular Localization
- Plasma membrane, Vesicles
- Introduction
- CD47 (CD47 Molecule) is a Protein Coding gene. Diseases associated with CD47 include Hereditary Spherocytosis and Neonatal Meningitis. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System. Gene Ontology (GO) annotations related to this gene include thrombospondin receptor activity.
- Alternative Names
- IAP, MER6, OA3
- Gene ID
- 961
- UniProt ID
- Q08722
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Datasheet
MSDS
COA
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See other products for "CD47"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-278LC | Human Anti-CD47 Recombinant Antibody (TAB-278LC) | Block, FuncS | Human IgG, κ |
| TAB-279LC | Human Anti-CD47 Recombinant Antibody (TAB-279LC) | Block, FuncS | Human IgG, κ |
| TAB-278LC-S(P) | Human Anti-CD47 Recombinant Antibody; scFv Fragment (TAB-278LC-S(P)) | ELISA | Human scFv |
| TAB-278LC-F(E) | Human Anti-CD47 Recombinant Antibody; Fab Fragment (TAB-278LC-F(E)) | ELISA | Human Fab |
| TAB-279LC-F(E) | Human Anti-CD47 Recombinant Antibody; Fab Fragment (TAB-279LC-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-280LC | Human Anti-CD47 Recombinant Antibody (TAB-280LC) | ELISA | Humanized antibody |
| TAB-281LC | Human Anti-CD47 Recombinant Antibody (TAB-281LC) | ELISA | Humanized antibody |
| TAB-282LC | Human Anti-CD47 Recombinant Antibody (TAB-282LC) | ELISA | Humanized antibody |
| TAB-283LC | Human Anti-CD47 Recombinant Antibody (TAB-283LC) | ELISA | Humanized antibody |
| TAB-284LC | Human Anti-CD47 Recombinant Antibody (TAB-284LC) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-387CQ | Mouse Anti-CD47 Recombinant Antibody (clone CBL377) | Block, FC, CyTOF | Mouse IgG1 |
| NEUT-388CQ | Mouse Anti-CD47 Recombinant Antibody (clone MIAP410) | Block, IF | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-389CQ | Rat Anti-CD47 Recombinant Antibody (clone miap301) | FC, FuncS, Neut, WB | Rat IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0565 | Hi-Affi™ Rabbit Anti-CD47 Recombinant Antibody (clone DS565AB) | WB, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0008-FY-F(E) | Human Anti-CD47 Recombinant Antibody; Fab Fragment (HPAB-0008-FY-F(E)) | ELISA | Humanized Fab |
| HPAB-M0269-YC-F(E) | Human Anti-CD47 Recombinant Antibody (clone M/YC-18); Fab Fragment | ELISA, WB | Humanized Fab |
| HPAB-M0300-YC-F(E) | Mouse Anti-CD47 Recombinant Antibody; Fab Fragment (HPAB-M0300-YC-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-M0301-YC-F(E) | Mouse Anti-CD47 Recombinant Antibody; Fab Fragment (HPAB-M0301-YC-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-M0302-YC-F(E) | Mouse Anti-CD47 Recombinant Antibody; Fab Fragment (HPAB-M0302-YC-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1082LY-S(P) | Human Anti-CD47 Recombinant Antibody; scFv Fragment (HPAB-1082LY-S(P)) | ELISA | Human scfv |
| HPAB-1083LY-S(P) | Human Anti-CD47 Recombinant Antibody; scFv Fragment (HPAB-1083LY-S(P)) | ELISA | Human scfv |
| HPAB-1084LY-S(P) | Human Anti-CD47 Recombinant Antibody; scFv Fragment (HPAB-1084LY-S(P)) | ELISA | Human scfv |
| HPAB-1085LY-S(P) | Human Anti-CD47 Recombinant Antibody; scFv Fragment (HPAB-1085LY-S(P)) | ELISA | Human scfv |
| HPAB-1086LY-S(P) | Human Anti-CD47 Recombinant Antibody; scFv Fragment (HPAB-1086LY-S(P)) | ELISA | Human scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1082LY | Human Anti-CD47 Recombinant Antibody (HPAB-1082LY) | ELISA | Human IgG |
| HPAB-1083LY | Human Anti-CD47 Recombinant Antibody (HPAB-1083LY) | ELISA | Human IgG |
| HPAB-1084LY | Human Anti-CD47 Recombinant Antibody (HPAB-1084LY) | ELISA | Human IgG |
| HPAB-1085LY | Human Anti-CD47 Recombinant Antibody (HPAB-1085LY) | ELISA | Human IgG |
| HPAB-1086LY | Human Anti-CD47 Recombinant Antibody (HPAB-1086LY) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0310-CN | Mouse Anti-CD47 Recombinant Antibody (clone 1A9) | IF, IHC, FC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP496-YC | Recombinant Alpaca Anti-CD47 Single Domain Antibody (HPAB-AP496-YC) | FC, BL, FuncS | Alpaca VHH |
| HPAB-AP497-YC | Recombinant Alpaca Anti-CD47 Single Domain Antibody (HPAB-AP497-YC) | FC | Alpaca VHH |
| HPAB-AP498-YC | Recombinant Alpaca Anti-CD47 Single Domain Antibody (HPAB-AP498-YC) | FC, BL | Alpaca VHH |
| HPAB-AP499-YC | Recombinant Alpaca Anti-CD47 Single Domain Antibody (HPAB-AP499-YC) | FC, BL | Alpaca VHH |
| NBD-0016-YJ-VHH | Camelid Anti-CD47 Recombinant Single Domain Antibody (NBD-0016-YJ-VHH) | ELISA, SPR | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY99 | Mouse Anti-NHP CD47 Recombinant Antibody (clone MEM-122) | FC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY55 | CytoStream™ Mouse Anti-CD47 Recombinant Antibody (clone B6H12) | FC | Mouse IgG1, kappa |
| VS-0225-XY56 | CytoStream™ Mouse Anti-CD47 Recombinant Antibody (clone CC2C6) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1191 | Anti-CD47 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1192 | Anti-Human CD47 Immunohistochemistry Kit | IHC |
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