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Mouse Anti-CD63 Recombinant Antibody (clone H5C6) (CAT#: VS3-CJ528)

This product is a mouse antibody that recognizes human CD63.


See more Engineered Antibody products for CD63
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  • Gene Expression
  • Datasheet
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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line SK-MEL-30
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73506/1798_B5_1_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26356/if_selected.jpg
Figure 3 IHC staining of human bone marrow
Figure 3 IHC staining of human bone marrow
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in subsets of bone marrow poietic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10088/ihc_selected.jpg
Figure 4 IHC staining of human placenta
Figure 4 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26356/ihc_selected.jpg
Normal Tissue
Figure 5 Liver
Figure 5 Liver
(Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10088/26867_A_9_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Collecting ducts
Staining:Medium
Intensity: Strong
Quantity: <25%
Distal tubules
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10088/26867_A_7_5.jpg
Figure 7 Testis
Figure 7 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10088/26867_A_4_6.jpg
Figure 8 Bone marrow
Figure 8 Bone marrow
(Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10088/26880_B_6_4.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (ASC diff)
Figure 9 RNA cell line category: Cell line enhanced (ASC diff)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000135404-CD63

Specifications

  • Immunogen
  • Native purified human CD63
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • Human CD63
  • Species Reactivity
  • Human
  • Clone
  • H5C6
  • Applications
  • IF, FC
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Affinity chromatography
  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Buffer
  • PBS, pH 7.3.
  • Preservative
  • 0.02% Sodium Azide
  • Storage
  • Store at 4°C for one year. Do not freeze.
  • Shipping
  • Shipped at 4°C

Applications

  • Application Notes
  • This antibody has been tested for use in Immunofluorescence, Flow Cytometry.

Target

  • Alternative Names
  • MLA1; ME491; LAMP-3; OMA81H; TSPAN30
  • Sequence Similarities
  • Belongs to the tetraspanin (TM4SF) family.
  • Cellular Localization
  • Cell membrane, Endosome, Lysosome, Membrane, Secreted
  • Post Translation Modifications
  • Palmitoylated at a low, basal level in unstimulated platelets. The level of palmitoylation increases when platelets are activated by thrombin (in vitro).
  • Function
  • Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.

Recommended Products

Isotype Control

Secondary Antibody

Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CD63"

Recombinant Antibody

CAT Product Name Application Type
MOB-1956z Mouse Anti-CD63 Recombinant Antibody (clone 38C9) WB, ELISA, FC, ICC, IF, IP, Dot, FuncS Mouse IgG1, κ
ZG-1062F Mouse Anti-CD63 Recombinant Antibody (clone NKI-Beteb) IHC-Fr, IHC-P Mouse IgG2b
ZG-1063F Mouse Anti-CD63 Recombinant Antibody (clone NKI-C3) ELISA, IF, IHC-Fr, IHC-P Mouse IgG1
VS3-FY308 Recombinant Rabbit Anti-Cd63 Antibody (clone R06-4G3) WB, IHC-P Rabbit IgG
VS3-FY309 Recombinant Mouse Anti-CD63 Antibody (clone 8H1-8H6-5G7) IHC-P Mouse IgG2a

Mouse Antibody

CAT Product Name Application Type
TAB-327LC Anti-Human CD63 Recombinant Antibody (NIBR63/1) FC, Inhib
TAB-328LC Anti-Human CD63 Recombinant Antibody (NIBR63/2) FC, Inhib
TAB-327LC-S(P) Anti-Human CD63 Recombinant Antibody scFv Fragment (NIBR63/1) FC
TAB-328LC-S(P) Anti-Human CD63 Recombinant Antibody scFv Fragment (NIBR63/2) FC
TAB-329LC-S(P) Anti-Human CD63 Recombinant Antibody scFv Fragment (NIBR63/3) FC

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0575 Hi-Affi™ Rabbit Anti-CD63 Recombinant Antibody (clone DS575AB) WB, IHC Rabbit IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0071-YJ-S(P) Human Anti-CD63 Recombinant Antibody (clone Hu33-11A); scFv Fragment FC, ELISA, IHC Humanized scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0071-YJ-F(E) Human Anti-CD63 Recombinant Antibody (clone Hu33-11A); Fab Fragment FC, ELISA, IHC Humanized Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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