This product is a recombinant antibody that recognizes CD79b. The monoclonal antibody huMA79b reacts with the epitope of CD79b.
Figure 1 Shows a graph of inhibition of in vivo tumor growth in a BJAB-luciferase xenograft mode.
Administration of anti-CD79b antibodies/chMA79b-SMCC-DM1, drug load was approximately 2.9 and huMA79b L2/H3-SMCC-DM1, drug load was approximately 2.4 to SCID mice having human B cell tumors significantly inhibited tumor growth.
Figure 2 Shows a graph of inhibition of in vivo tumor growth in a Granta-519 (Human Mantle Cell Lymphoma) xenograft model.
Administration of anti-CD79b antibodies/chMA79b-SMCC-DM1, drug load was approximately 3.6 and huMA79b.v17-SMCC-DM1, drug load was approximately 3.4 to SCID mice having human B cell tumors significantly inhibited tumor growth.
Figure 3 Shows a graph of inhibition of in vivo tumor growth in a BJAB-luciferase (Burkitt's Lymphoma) xenograft model.
Administration of anti-CD79b TDCs conjugated to different linker drug moieties or anti-CD79b antibody (huMA79b) to SCID mice having human B cell tumors, significantly inhibited tumor growth.
Figure 4 Shows a graph of inhibition of in vivo tumor growth in a WSU-DLCL2 (Diffuse Large Cell Lymphoma) xenograft model .
Administration of anti-CD79b TDCs conjugated to different linker drug moieties or anti-CD79b antibody (huMA79b) to SCID mice having human B cell tumors, significantly inhibited tumor growth.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-897 | Humanized Anti-CD79B Recombinant Antibody (clone Polatuzumab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | Humanized (from mouse) IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0581 | Hi-Affi™ Rabbit Anti-CD79B Recombinant Antibody (clone DS581AB) | WB, IHC, ICC, IP, FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC1918 | PE-A*02:01/Human CD79B (LLSAEPVPA) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-027LC | Recombinant Mouse Anti-M.fascicularis CD79B Antibody | ELISA, FuncS | Mouse IgG |
FAMAB-0058YC | Hamster Anti-Cd79b Recombinant Antibody (clone HM79-16) | FuncS | Hamster IgG |
HPAB-0364LY | Human Anti-CD79B Recombinant Antibody (HPAB-0364LY) | Inhib, ELISA | Human IgG |
FN-062CQ | Mouse Anti-CD79B Recombinant Antibody (clone SN8) | FC, FuncS, WB | Mouse IgG1, κ |
HPAB-1938-FY | Mouse Anti-CD79B Recombinant Antibody (clone MA79b) | FuncS, FC | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0058-YC-S(P) | Hamster Anti-Cd79b Recombinant Antibody (clone HM79-16); scFv Fragment | FuncS | Hamster scFv |
HPAB-N0044-YC-S(P) | Human Anti-CD79b Recombinant Antibody; scFv Fragment (HPAB-N0044-YC-S(P)) | FuncS | Humanized scFv |
HPAB-1059-FY-F(E) | Mouse Anti-CD79B Recombinant Antibody; Fab Fragment (HPAB-1059-FY-F(E)) | FC | Mouse Fab |
HPAB-J0055-YC-S(P) | Human Anti-CD79B Recombinant Antibody; scFv Fragment (HPAB-J0055-YC-S(P)) | ELISA, FC, Inhib, FuncS | Humanized scFv |
HPAB-1939-FY-S(P) | Human Anti-CD79B Recombinant Antibody (clone huMA79b); scFv Fragment | ELISA, FC, FuncS | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0058-YC-F(E) | Hamster Anti-Cd79b Recombinant Antibody (clone HM79-16); Fab Fragment | FuncS | Hamster Fab |
HPAB-618-FY-F(E) | Human Anti-CD79B Recombinant Antibody; Fab Fragment (HPAB-618-FY-F(E)) | FC, ELISA | Humanized Fab |
HPAB-619-FY-F(E) | Human Anti-CD79B Recombinant Antibody; Fab Fragment (HPAB-619-FY-F(E)) | FC, ELISA | Humanized Fab |
HPAB-N0044-YC-F(E) | Human Anti-CD79b Recombinant Antibody; Fab Fragment (HPAB-N0044-YC-F(E)) | FuncS | Humanized Fab |
HPAB-1938-FY-F(E) | Mouse Anti-CD79B Recombinant Antibody (clone MA79b); Fab Fragment | ELISA, FC, FuncS | Mouse Fab, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-897 | Afuco™ Anti-CD79B ADCC Recombinant Antibody (Polatuzumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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