Rabbit Anti-CD8B Recombinant Antibody (VS-1225-XY67)
CAT#: VS-1225-XY67
It serves as a core research tool targeting CD8B, performing consistently in ELISA, WB, and IHC. This antibody streamlines experimental workflows for CD8B detection in normal and pathological samples.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line CACO-2
Immunofluorescent staining of human cell line CACO-2 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29164/1526_E8_1_selected.jpg
Normal Tissue
Figure 2 High expression in lymph node.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4353/165972_A_9_8_val_selected.jpg
Normal Tissue
Figure 3 Low expression in liver.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4353/165972_A_9_4_val_selected.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4353/165972_A_9_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enriched (RPMI-8226)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000172116-CD8B
❮
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Specifications
- Host Animal
- Rabbit
- Applications
- FC, SPR
- Specificity
- CD8B
- Target
- CD8B
- Species Reactivity
- Human
- Type
- Rabbit IgG
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Protein A purified
- Format
- Liquid
- Buffer
- PBS, pH 7.3
- Preservative
- 0.09% sodium azide
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
- Alternative Names
- LY3, P37, LEU2, LYT3, Ly-3, CD8B1, CD8beta
- Gene ID
- 926
- UniProt ID
- P10966
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Recommended Dilution Buffer
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- Product Name
Secondary Antibody
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Isotype Control
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
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| FAMAB-0012-CN-S(P) | Mouse Anti-CD8B Recombinant Antibody (clone EP42); scFv Fragment | FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0012-CN-F(E) | Mouse Anti-CD8B Recombinant Antibody (clone EP42); Fab Fragment | FC | Mouse Fab |
| CAT | Product Name | Application | Type |
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| FN-198CQ | Mouse Anti-CD8B Recombinant Antibody (clone 341) | Neut, FC, FuncS, IHC-P | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
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| HPAB-S0182-YC | Rat Anti-Cd8b1 Recombinant Antibody (clone YTS156.7.7) | Neut | Rat IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-S0182-YC-F(E) | Rat Anti-Cd8b1 Recombinant Antibody (clone YTS156.7.7); Fab Fragment | Neut | Rat Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-S0182-YC-S(P) | Rat Anti-Cd8b1 Recombinant Antibody (clone YTS156.7.7); scFv Fragment | Neut | Rat scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1681CQ | Mouse Anti-CD8B Recombinant Antibody (clone YTS 156.7.7) | FC, IHC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY80 | CytoStream™ Mouse Anti-CD8B Recombinant Antibody (clone 2ST8.5H7) | FC | Mouse IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY185 | Rat Anti-CD8B (clone YTS156.7.7) scFv-Fc Chimera | FC | Rat IgG2b, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC445 | Recombinant Anti-CD8B Vesicular Antibody, EV Displayed (VS-0425-YC445) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1242 | Anti-CD8B Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1243 | Anti-Human CD8B Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1244 | Anti-Rat CD8B Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY64 | Mouse Anti-CD8B Recombinant Antibody (VS-1225-XY64) | WB, IHC, FC, IP | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY65 | Mouse Anti-CD8B Recombinant Antibody (VS-1225-XY65) | IHC, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY66 | Mouse Anti-CD8B Recombinant Antibody (VS-1225-XY66) | IHC, FC, IP | Mouse IgG1 |
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