Human Anti-CR1 Recombinant Antibody (clone E11) (CAT#: FAMAB-1103CQ)
This product is a recombinant human antibody that recognizes CR1. The antibody was purified by affinity chromatography. It can be used in WB, ELISA, IF.
Specific Inquiry
IF
Figure 1 CR1 expressed by CHO cells is recognized by anti-CR1 antibodies.
CR1 immunofluorescence staining using mouse mAbs E11 on fixed CHO cells. Scale bar: 50 μm.
Fonseca, M. I., Chu, S., Pierce, A. L., Brubaker, W. D., Hauhart, R. E., Mastroeni, D., ... & Tenner, A. J. (2016). Analysis of the putative role of CR1 in Alzheimer’s disease: genetic association, expression and function. PloS one, 11(2), e0149792.
IP
Figure 2 Immunoprecipitation of CR1 with mAb E11.
Immunoprecipitates of E11 (4 μg) (lanes 3, 5, 7) or IgG1 (4 μg) (lanes 2, 4, 6) with sCR1 (2 μg) (lanes 2,3), RBC from a MCI subject (TT/GG) (50 μg protein, lane 4, 5) or brain extracts from cognitively intact subject (AT/AG) (250 μg, lane 6, 7). sCR1 isloaded at 1 ng (lane 1).
Fonseca, M. I., Chu, S., Pierce, A. L., Brubaker, W. D., Hauhart, R. E., Mastroeni, D., ... & Tenner, A. J. (2016). Analysis of the putative role of CR1 in Alzheimer’s disease: genetic association, expression and function. PloS one, 11(2), e0149792.
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Species Reactivity
- Human
- Clone
- E11
- Applications
- IF, IP
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Immunoprecipitation and Immunofluorescence.
Target
- Alternative Names
- Complement C3b/C4b Receptor 1 (Knops Blood Group); Complement Component (3b/4b) Receptor 1 (Knops Blood Group); C3b/C4b Receptor; CD35 Antigen; C3BR; Complement Component (3b/4b) Receptor 1, Including Knops Blood Group System; Complement Component 3b/4b Receptor 1 (Knops Blood Group)
- Gene ID
- 1378
- UniProt ID
- P17927
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-240-F(E) | Recombinant Anti-human CR1 Antibody Fab Fragment | WB, FACS, FuncS | Fab |
| MHH-240-F(E) | Recombinant Human Anti-human CR1 Antibody Fab Fragment | ELISA, Nert, FuncS | Fab |
| HPAB-0421-CN-F(E) | Mouse Anti-CR1 Recombinant Antibody (clone E11); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0422-CN-F(E) | Mouse Anti-CR1 Recombinant Antibody (clone EDIVH1/VL1); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0423-CN-F(E) | Mouse Anti-CR1 Recombinant Antibody (clone EDI19E9); Fab Fragment | ELISA, FC | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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