Afuco™ Anti-EGFL7 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-902)
CAT#: AFC-TAB-902
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized (from mouse) antibody expressed in CHO binding to human EGFL7. It is a humanized monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator and binds to EGFL7.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_B_8_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_7_3.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_8_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_5_6.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (EFO-21, HUVEC TERT2, RPMI-8226, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000172889-EGFL7
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- ELISA, IP, FC, FuncS, Neut
- Conjugate
- Unconjugated
- Generic Name
- Parsatuzumab
- Related Disease
- Solid tumors
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Biosimilar Overview
Please refer to Parsatuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Parsatuzumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "EGFL7"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-834-VHH | Recombinant Anti-Human EGFL7 VHH Single Domain Antibody | IHC, ICC, FC, FA, FUNC | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-902 | Anti-Human EGFL7 Recombinant Antibody (TAB-902) | Block | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2365MZ | Recombinant Mouse Anti-Human EGFL7 Antibody | WB | Mouse antibody |
| HPAB-0001-DJB | Mouse Anti-EGFL7 Recombinant Antibody (HPAB-0001-DJB) | ELISA, WB | Mouse IgG2b |
| HPAB-0002-DJB | Mouse Anti-EGFL7 Recombinant Antibody (HPAB-0002-DJB) | ELISA, WB | Mouse IgG2b |
| HPAB-0003-DJB | Mouse Anti-EGFL7 Recombinant Antibody (HPAB-0003-DJB) | ELISA, WB | Mouse IgG2b |
| VS-0224-XY40 | Mouse Anti-EGFL7 Recombinant Antibody (VS-0224-XY40) | ELISA, WB, FC, IF, IP | Human IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0001-DJB-S(P) | Mouse Anti-EGFL7 Recombinant Antibody scFv Fragment (HPAB-0001-DJB-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0002-DJB-S(P) | Mouse Anti-EGFL7 Recombinant Antibody scFv Fragment (HPAB-0002-DJB-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0003-DJB-S(P) | Mouse Anti-EGFL7 Recombinant Antibody; scFv Fragment (HPAB-0003-DJB-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0951WJ-S(P) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v1); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0952WJ-S(P) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v17); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0001-DJB-F(E) | Mouse Anti-EGFL7 Recombinant Antibody Fab Fragment (HPAB-0001-DJB-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0002-DJB-F(E) | Mouse Anti-EGFL7 Recombinant Antibody Fab Fragment (HPAB-0002-DJB-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0003-DJB-F(E) | Mouse Anti-EGFL7 Recombinant Antibody; Fab Fragment (HPAB-0003-DJB-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0951WJ-F(E) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v1); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0952WJ-F(E) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v17); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY102 | Mouse Anti-EGFL7 (clone 18F7.v6) scFv-Fc Chimera | Inhib | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC63 | Recombinant Anti-EGFL7 (AA 66-69 x AA 88-90) Biparatopic Antibody, Tandem scFv | ELISA, WB | Tandem scFv |
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