Afuco™ Anti-EGFL7 ADCC Recombinant Antibody (Parsatuzumab), ADCC Enhanced (CAT#: AFC-TAB-902)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized (from mouse) antibody expressed in CHO binding to human EGFL7. Parsatuzumab is a humanized monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator and binds to EGFL7.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_B_8_5.jpg
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_B_8_5.jpg
Figure 2 Colon
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_7_3.jpg
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_7_3.jpg
Figure 3 Liver
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_8_4.jpg
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_8_4.jpg
Figure 4 Kidney
(Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_8_5.jpg
(Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_8_5.jpg
Figure 5 Testis
(Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_5_6.jpg
(Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_5_6.jpg
Figure 6 Lymph node
(Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_7_8.jpg
(Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50716/118119_A_7_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (EFO-21, HUVEC TERT2, RPMI-8226, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000172889-EGFL7
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000172889-EGFL7
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Parsatuzumab
- Applications
- ELISA, IP, FC, FuncS, Neut
- Conjugate
- Unconjugated
- Generic Name
- Parsatuzumab
- Related Disease
- Solid tumors
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Parsatuzumab; 1312797-14-0; RG7414; MEGF0444A; EGFL7; EGF-like-domain, multiple 7; epidermal growth factor-like protein 7; ZNEU1; EGF-like protein 7; NOTCH4-like protein; vascular endothelial statin; multiple EGF-like domains protein 7;
- Gene ID
- 51162
- UniProt ID
- Q9UHF1
Related Resources
Please refer to Parsatuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Parsatuzumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Parsatuzumab"
Anti-Human EGFL7 Recombinant Antibody (Parsatuzumab)Recombinant humanized (from mouse) antibody expressed in CHO binding to human EGFL7. Parsatuzumab is a humanized monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator and binds to EGFL7.
See other products for "EGFL7"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-834-VHH | Recombinant Anti-Human EGFL7 VHH Single Domain Antibody | IHC, ICC, FC, FA, FUNC | Llama VHH |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-902 | Anti-Human EGFL7 Recombinant Antibody (Parsatuzumab) | Block | IgG1 - kappa |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2365MZ | Recombinant Mouse Anti-Human EGFL7 Antibody | WB | Mouse antibody |
| HPAB-0001-DJB | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11) | ELISA, WB | Mouse IgG2b |
| HPAB-0002-DJB | Mouse Anti-EGFL7 Recombinant Antibody (clone 10G9) | ELISA, WB | Mouse IgG2b |
| HPAB-0003-DJB | Mouse Anti-EGFL7 Recombinant Antibody (HPAB-0003-DJB) | ELISA, WB | Mouse IgG2b |
| HPAB-0951WJ | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v1) | ELISA | Mouse IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0001-DJB-S(P) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11); scFv Fragment | ELISA, WB | Mouse scFv |
| HPAB-0002-DJB-S(P) | Mouse Anti-EGFL7 Recombinant Antibody (clone 10G9); scFv Fragment | ELISA, WB | Mouse scFv |
| HPAB-0951WJ-S(P) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v1); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0952WJ-S(P) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v17); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0953WJ-S(P) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v22); scFv Fragment | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0001-DJB-F(E) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11); Fab Fragment | ELISA, WB | Mouse Fab |
| HPAB-0002-DJB-F(E) | Mouse Anti-EGFL7 Recombinant Antibody (clone 10G9); Fab Fragment | ELISA, WB | Mouse Fab |
| HPAB-0003-DJB-F(E) | Mouse Anti-EGFL7 Recombinant Antibody; Fab Fragment (HPAB-0003-DJB-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0951WJ-F(E) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v1); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0952WJ-F(E) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v17); Fab Fragment | ELISA | Mouse Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for AFC-TAB-902. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.