Afuco™ Anti-FGF23 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-010ML)
CAT#: AFC-TAB-010ML
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to FGF23. It is a human monoclonal antibody that can be potentially used in the treatment of Dermatological genetic disorders, Hypophosphatemia, Tumor Induced Osteomalacia (TIO), Epidermal Nevus Syndrome (ENS), X-linked (Hereditary hypophosphatemic rickets), Osteomalacia, oncogenic.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (AF22, HBEC3-KT)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000118972-FGF23
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Specificity
- Human FGF23
- Species Reactivity
- Human
- Applications
- ELISA, IHC, FC, IP, IF, Inhib
- Conjugate
- Unconjugated
- Generic Name
- Burosumab
- Related Disease
- Dermatological genetic disorders, Hypophosphatemia, Tumor Induced Osteomalacia (TIO), Epidermal Nevus Syndrome (ENS), X-linked (Hereditary hypophosphatemic rickets), Osteomalacia, oncogenic
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Biosimilar Overview
Please refer to Burosumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Burosumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Burosumab"
DrugMonitor™ Anti-Burosumab Antibody (VS-1224-YC233)Burosumab (KRN23) is a fully human IgG1 monoclonal antibody that binds FGF23, successfully tested in clinical trials for children with X-linked hypophosphatemic rickets. The DrugMonitor™ Anti-Burosumab Antibody (VS-1224-YC233) is an anti-drug antibody (ADA) against Burosumab. This drug-based antibody is raised in mice immunized with the Burosumab. The anti-Burosumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Burosumab in samples.
See other products for "FGF23"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2776z | Mouse Anti-FGF23 Recombinant Antibody (clone 33H1) | WB, ELISA, ICC, IHC | Mouse IgG |
| HPAB-0207-YC | Human Anti-FGF23 Recombinant Antibody (HPAB-0207-YC) | ELISA, FuncS | Human IgG |
| MOB-145YJL | Rat Anti-FGF23 Recombinant Antibody (clone CBF850) | WB, ELISA | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-010ML | Anti-Human FGF23 Recombinant Antibody (TAB-010ML) | ELISA, IHC, FC, IP, IF, Inhib | IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0207-YC-S(P) | Human Anti-FGF23 Recombinant Antibody; scFv Fragment (HPAB-0207-YC-S(P)) | ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0207-YC-F(E) | Human Anti-FGF23 Recombinant Antibody; Fab Fragment (HPAB-0207-YC-F(E)) | ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY107 | Human Anti-FGF23 scFv-Fc Chimera (VS-0425-FY107) | ELISA, FC, Neut | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2527 | Anti-FGF23 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2528 | Anti-Mouse FGF23 Immunohistochemistry Kit | IHC |
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