CytoStream™ Rabbit Anti-FOS Recombinant Antibody (VS13-YC410)
CAT#: VS13-YC410
The CytoStream™ Rabbit Anti-FOS Recombinant Antibody is specific for human, mouse and rat FOS. FOS family proteins, like FOS and FOSL, form AP-1 complexes, regulating cellular proliferation and transformation, involved in apoptosis and differentiation processes through leucine zipper domain interactions. The anti-FOS antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18531/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human adrenal gland
Immunohistochemical staining of human adrenal gland shows strong nuclear and cytoplasmic positivity in cortical cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18531/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18531/42814_B_8_5.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18531/42814_A_8_4.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (hTCEpi, OE19)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000170345-FOS
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Specifications
- Immunogen
- Recombinant human c-Fos, aa 231-268.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat FOS
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC-P, FC
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500
Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- Fos Proto-Oncogene, AP-1 Transcription Factor Subunit; FBJ Murine Osteosarcoma Viral Oncogene Homolog; G0/G1 Switch Regulatory Protein 7; FBJ Murine Osteosarcoma Viral (V-Fos) Oncogene Homolog (Oncogene FOS); V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog; Fos Proto-Oncogene, AP-1 Trancription Factor Subunit; Cellular Oncogene C-Fos; Cellular Oncogene Fos;
- Gene ID
- 2353
- UniProt ID
- P01100
- Long Name
- Fos Proto-Oncogene, AP-1 Transcription Factor Subunit
- Cellular Localization
- Nucleus; Endoplasmic reticulum; Cytoplasm
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Related Diseases
Colorectal Cancer
Endometrial Cancer
Gastric Cancer
Non-small Cell Lung Cancer
Insulin Resistance
Related Signaling Pathways
NLR Signaling Pathway
TNF Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "FOS"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0207MZ | Chicken Anti-c-Fos Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1335 | Hi-Affi™ Rabbit Anti-FOS Recombinant Antibody (clone DS1335AB) | WB, FC | Rabbit IgG |
| MOR-0103-FY | Rabbit Anti-FOS Recombinant Antibody (clone AFY0074) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0355-CN | Rabbit Anti-FOS Recombinant Antibody (clone JJ0938) | WB, FC | Rabbit IgG |
| ZG-0415F | Mouse Anti-FOS Recombinant Antibody (ZG-0415F) | WB | Mouse IgG |
| ZG-0386U | Rabbit Anti-FOS Recombinant Antibody (clone F14-R) | ELISA, WB, IP, ICC | Rabbit IgG |
| ZG-0387U | Rabbit Anti-FOS Recombinant Antibody (clone A16-L) | ELISA, WB, IP | Rabbit IgG |
| ZG-0402U | Rabbit Anti-FOS Recombinant Antibody (clone I24-V) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2610 | Anti-FOS Immunohistochemistry Kit | IHC | |
| VS-0525-XY2611 | Anti-Mouse FOS Immunohistochemistry Kit | IHC | |
| VS-0525-XY2612 | Anti-Rat FOS Immunohistochemistry Kit | IHC |
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