Mouse Anti-GDF15 Recombinant Antibody (clone MBM-12)
CAT#: HPAB-0395-YJ
This product is a recombinant mouse antibody that recognizes human GDF15. It inhibits the induction of angiogenesis by MIC-1.
Published Data
Gene Expression
ELISA
Figure 1 Anti-MIC-1 scFv Antibody Detection by Phage-display Method.
Inhib
Figure 2 Inhibition of endothelial cell activation promoting function of MIC-1 by scFv monoclonal antibody.
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Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11191/1404_F3_1_selected.jpg
Normal Tissue
Figure 2 Placenta
Cytotrophoblasts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining: High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining: High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11191/27866_A_1_7.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (BEWO, Hep G2, HHSteC, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130513-GDF15
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Specifications
- Immunogen
- Recombinant MIC-1 protein
- Host Species
- Mouse
- Derivation
- scFv phage display library
- Type
- Mouse IgG
- Specificity
- Human GDF15
- Species Reactivity
- Human
- Clone
- MBM-12
- Applications
- ELISA, Inhib
- Conjugate
- Unconjugated
- Related Disease
- Tumor
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Inhibition.
Target
- Alternative Names
- PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15; growth/differentiation factor 15; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PTGF-beta; macrophage inhibitory cytokine 1; non-steroidal anti-inflammatory drug-activated gene-1; placental TGF-beta; placental bone morphogenetic protein; prostate differentiation factor
- Gene ID
- 9518
- UniProt ID
- Q99988
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone MBM-12"
- CAT
- Product Name
See other products for "GDF15"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-391 | Recombinant Anti-human GDF15 Antibody | ELISA, WB, IF, FuncS | IgG |
| MHH-391 | Recombinant Human Anti-human GDF15 Antibody | ELISA, WB, FuncS | IgG |
| MOB-0141CT | Recombinant Mouse anti-Human GDF15 Monoclonal antibody (NN0408-20B4) | FC, WB | |
| HPAB-0334-CN | Mouse Anti-GDF15 Recombinant Antibody (HPAB-0334-CN) | ELISA, WB | Mouse IgG1, κ |
| HPAB-0335-CN | Mouse Anti-GDF15 Recombinant Antibody (HPAB-0335-CN) | ELISA, WB | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-391-S(P) | Recombinant Anti-human GDF15 Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| HPAB-0334-CN-S(P) | Mouse Anti-GDF15 Recombinant Antibody; scFv Fragment (HPAB-0334-CN-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0335-CN-S(P) | Mouse Anti-GDF15 Recombinant Antibody; scFv Fragment (HPAB-0335-CN-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0336-CN-S(P) | Mouse Anti-GDF15 Recombinant Antibody; scFv Fragment (HPAB-0336-CN-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0337-CN-S(P) | Human Anti-GDF15 Recombinant Antibody; scFv Fragment (HPAB-0337-CN-S(P)) | ELISA, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0781CL | Anti-Human GDF15 Recombinant Antibody | ELISA, WB | Humanized antibody |
| TAB-0781CL-S(P) | Anti-Human GDF15 Recombinant Antibody scFv Fragment | ELISA, WB | Humanized antibody |
| TAB-0781CL-F(E) | Anti-Human GDF15 Recombinant Antibody Fab Fragment | ELISA, WB | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0784CL | Human Anti-GDF15 Recombinant Antibody (TAB-0784CL) | ELISA, FC | Human IgG |
| TAB-0784CL-S(P) | Human Anti-GDF15 Recombinant Antibody; scFv Fragment (TAB-0784CL-S(P)) | ELISA, FC | Human scFv |
| TAB-0784CL-F(E) | Human Anti-GDF15 Recombinant Antibody; Fab Fragment (TAB-0784CL-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0782CL-S(P) | Anti-Human GDF15 Recombinant Antibody scFv Fragment (A10.3) | ELISA, FC | |
| TAB-0783CL-S(P) | Anti-Human GDF15 Recombinant Antibody scFv Fragment (B2.2) | ELISA, FC | |
| TAB-0785CL-S(P) | Mouse Anti-GDF15 Recombinant Antibody; scFv Fragment (TAB-0785CL-S(P)) | ELISA, FC, WB | Mouse scFv |
| TAB-0786CL-S(P) | Mouse Anti-GDF15 Recombinant Antibody; scFv Fragment (TAB-0786CL-S(P)) | ELISA, FC, WB | Mouse scFv |
| TAB-0787CL-S(P) | Mouse Anti-GDF15 Recombinant Antibody; scFv Fragment (TAB-0787CL-S(P)) | ELISA, FC, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1421 | Hi-Affi™ Rabbit Anti-GDF15 Recombinant Antibody (clone DS1421AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0522-YC-F(E) | Human Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-M0522-YC-F(E)) | ELISA, Block | Human Fab |
| HPAB-M0523-YC-F(E) | Human Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-M0523-YC-F(E)) | ELISA, Block | Human Fab |
| HPAB-M0524-YC-F(E) | Human Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-M0524-YC-F(E)) | ELISA, Block | Human Fab |
| HPAB-M0525-YC-F(E) | Human Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-M0525-YC-F(E)) | ELISA, Block | Human Fab |
| HPAB-M0526-YC-F(E) | Human Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-M0526-YC-F(E)) | ELISA, Block | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2774 | Anti-GDF15 Immunohistochemistry Kit | IHC |
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