Mouse Anti-GP6 Recombinant Antibody (clone 12A5) (CAT#: FAMAB-0101JF)
Recombinant mouse monoclonal antibody specially binds to platelet glycoprotein VI (GPVI). This anti-GPVI antibody 12A5 can be useful in the treatment of immune thrombocytopenic purpura (ITP).
Specific Inquiry
WB
Figure 1 Western blot of the fractions developed with antibodies against gp6, gp15 and gp16.
Connector proteins co-sediment in fractions 7 to 9.
Lurz, R., Orlova, E. V., Günther, D., Dube, P., Dröge, A., Weise, F., ... & Tavares, P. (2001). Structural organisation of the head-to-tail interface of a bacterial virus. Journal of molecular biology, 310(5), 1027-1037.
IHC
Figure 2 Position of gp6 in the head-to-tail interface.
The bar represents 100 nm.
Lurz, R., Orlova, E. V., Günther, D., Dube, P., Dröge, A., Weise, F., ... & Tavares, P. (2001). Structural organisation of the head-to-tail interface of a bacterial virus. Journal of molecular biology, 310(5), 1027-1037.
ELISA
Figure 3 ELISA based on GP6 coating antigens.
Detection of specific immunoglobulins to the gp6 proteins in sera of women.
Di Bonito, P., Grasso, F., Mochi, S., Accardi, L., Donà, M. G., Branca, M., ... & Syrjänen, K. (2006). Serum antibody response to Human papillomavirus (HPV) infections detected by a novel ELISA technique based on denatured recombinant HPV16 L1, L2, E4, E6 and E7 proteins. Infectious agents and cancer, 1(1), 6.
FC
Figure 4 Characteristic examples of the data recorded in response to the maximum stimulation with adenosine 5¢-diphosphate (or 2MeSADP).
Flow cytometry to illustrate the differences in the responses to the agonist.
Jones, C. I., Garner, S. F., Angenent, W., Bernard, A., Berzuini, C., Burns, P., ... & Tom, B. D. (2007). Mapping the platelet profile for functional genomic studies and demonstration of the effect size of the GP6 locus. Journal of Thrombosis and Haemostasis, 5(8), 1756-1765.
Specifications
- Immunogen
- GPVI
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human GPVI
- Species Reactivity
- Human
- Clone
- 12A5
- Applications
- WB, ELISA, IHC, FC
- Related Disease
- Immune thrombocytopenic purpura
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The GP6 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry, Flow Cytometry.
Target
- Alternative Names
- Glycoprotein VI Platelet; Glycoprotein VI (Platelet); Glycoprotein 6; GPVI; Platelet Collagen Recept; Platelet Glycoprotein VI; BDPLT11; GPIV
- Gene ID
- 51206
- UniProt ID
- Q9HCN6
- Function
- Blocking
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 12A5"
See other products for "GP6"
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-003CT | Anti-Human GPVI Recombinant Antibody (1C3) | Funcs, ELISA, Inhib, FC | Human antibody |
| TAB-003CT-S(P) | Anti-Human GPVI Recombinant Antibody scFv Fragment (1C3) | Funcs, ELISA, Inhib, FC | Human antibody |
| TAB-003CT-F(E) | Anti-Human GPVI Recombinant Antibody Fab Fragment (1C3) | ELISA, Inhibition, FC | Human antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-005CT | Mouse Anti-GP6 Recombinant Antibody (TAB-005CT) | WB, ELISA, Block | Mouse IgG1, κ |
| TAB-005CT-S(P) | Mouse Anti-GP6 Recombinant Antibody; scFv Fragment (TAB-005CT-S(P)) | WB, ELISA, Block | Mouse scFv |
| TAB-005CT-F(E) | Mouse Anti-GP6 Recombinant Antibody; Fab Fragment (TAB-005CT-F(E)) | WB, ELISA, Block | Mouse Fab |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1483 | Hi-Affi™ Rabbit Anti-GP6 Recombinant Antibody (clone DS1483AB) | WB | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1711-FY | Human Anti-GP6 Recombinant Antibody (clone F1245-4-1) | ELISA, WB, IHC | Chimeric (mouse/human) IgG |
| HPAB-1712-FY | Human Anti-GP6 Recombinant Antibody (clone F1245-5-1) | ELISA, WB, IHC | Chimeric (mouse/human) IgG |
| HPAB-1713-FY | Human Anti-GP6 Recombinant Antibody (clone F1245-6-2) | ELISA, WB, IHC | Chimeric (mouse/human) IgG |
| HPAB-1714-FY | Human Anti-GP6 Recombinant Antibody (clone F1232-7-1) | ELISA | Human IgG |
| HPAB-1715-FY | Human Anti-GP6 Recombinant Antibody (clone F1232-18-3) | ELISA | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1711-FY-F(E) | Mouse Anti-GP6 Recombinant Antibody (clone F1245-4-1); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
| HPAB-1712-FY-F(E) | Mouse Anti-GP6 Recombinant Antibody (clone F1245-5-1); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
| HPAB-1713-FY-F(E) | Mouse Anti-GP6 Recombinant Antibody (clone F1245-6-2); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
| HPAB-1714-FY-F(E) | Human Anti-GP6 Recombinant Antibody (clone F1232-7-1); scFv Fragment | ELISA | Human scFv |
| HPAB-1715-FY-F(E) | Human Anti-GP6 Recombinant Antibody (clone F1232-18-3); scFv Fragment | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1711-FY-S(P) | Human Anti-GP6 Recombinant Antibody (clone F1245-4-1); Fab Fragment | ELISA, WB, IHC | Chimeric (mouse/human) Fab |
| HPAB-1712-FY-S(P) | Human Anti-GP6 Recombinant Antibody (clone F1245-5-1); Fab Fragment | ELISA, WB, IHC | Chimeric (mouse/human) Fab |
| HPAB-1713-FY-S(P) | Human Anti-GP6 Recombinant Antibody (clone F1245-6-2); Fab Fragment | ELISA, WB, IHC | Chimeric (mouse/human) Fab |
| HPAB-1714-FY-S(P) | Human Anti-GP6 Recombinant Antibody (clone F1232-7-1); Fab Fragment | ELISA | Human Fab |
| HPAB-1715-FY-S(P) | Human Anti-GP6 Recombinant Antibody (clone F1232-18-3); Fab Fragment | ELISA | Human Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for FAMAB-0101JF. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.