AbPlus™ Anti-GZMB Magnetic Beads (Fv17)
CAT#: VS-0424-XY117
The AbPlus Anti-GZMB Magnetic Beads (Fv17) is an innovative affinity resin which is bound with anti-GZMB specific antibody (Fv17). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of GZMB protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 Bone marrow
Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3418/10586_B_4_4.jpg
Normal Tissue
Figure 2 Lymph node
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3418/10586_A_7_8.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (HMC-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100453-GZMB
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-GZMB specific antibody (Fv17)
- Target
- GZMB
- Target Species
- Human
- Antibody Clone
- Fv17
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis.
- Alternative Names
- C11; HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1
- Gene ID
- 3002
- UniProt ID
- P10144
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Related Diseases
Allograft Rejection
Autoimmune Thyroid Disease
Graft-versus-Host Disease
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "GZMB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-424-F(E) | Recombinant Anti-human GZMB Antibody Fab Fragment | IF, WB, FuncS | Fab |
| MHH-424-F(E) | Recombinant Human Anti-human GZMB Antibody Fab Fragment | RIA, IP, FuncS | Fab |
| FAMAB-0137-YC-F(E) | Human Anti-GZMB Recombinant Antibody (clone Fv17); Fab Fragment | ELISA, FC, WB, IP | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-424-S(P) | Recombinant Anti-human GZMB Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| MHH-424-S(P) | Recombinant Human Anti-human GZMB Antibody scFv Fragment | WB, Neut, FuncS | scFv |
| FAMAB-0137-YC-S(P) | Human Anti-GZMB Recombinant Antibody (clone Fv17); scFv Fragment | ELISA, FC, WB, IP | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-424 | Recombinant Human Anti-human GZMB Antibody | ELISA, IP, FuncS | IgG |
| FAMAB-0137YC | Human Anti-GZMB Recombinant Antibody (clone Fv17) | ELISA, FC, WB, IP | Human IgG |
| ZG-0701J | Rabbit Anti-GZMB Recombinant Antibody (clone 6A1) | ELISA, IHC, IF | Rabbit IgG |
| VS3-XY788 | Mouse Anti-GZMB Recombinant Antibody (clone 4G9) | WB, IP, IF, IHC | Mouse IgG1 |
| VS-0224-XY56 | Human Anti-GZMB Recombinant Antibody (VS-0224-XY56) | ELISA | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1551 | Rabbit Anti-GZMB Recombinant Antibody (clone DS1551AB) | IHC-P, ICC, IF, IP | Rabbit IgG |
| MOR-4582 | Rabbit Anti-GZMB Recombinant Antibody (clone TH94DS) | WB, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY231 | Mouse Anti-NHP GZMB Recombinant Antibody (clone GB11) | WB, IF, FC, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3000 | Anti-GZMB Immunohistochemistry Kit | IHC |
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