Human Anti-GZMB Recombinant Antibody (clone Fv17); Fab Fragment
CAT#: FAMAB-0137-YC-F(E)
Granzyme B, a neutral serine protease, has been demonstrated to be a pivotal molecule for protective immunity against viral infection and cellular malignant transformation. Provided are single-chain Fv antibodies specific for granzyme B, as versatile alternatives and complementary reagents to currently available monoclonal antibodies. Owing to the availability of its DNA sequence and large scale production capability, Fv17 should be a superior reagent for monitoring granzyme B expression in natural killer cells and antigen specific CD8 T cell immunity.
Gene Expression
Normal Tissue
Figure 1 Bone marrow
Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3418/10586_B_4_4.jpg
Normal Tissue
Figure 2 Lymph node
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3418/10586_A_7_8.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (HMC-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100453-GZMB
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Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human Fab
- Specificity
- Human GZMB
- Species Reactivity
- Human
- Clone
- Fv17
- Applications
- ELISA, FC, WB, IP
- Related Disease
- Virus infection
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Related Diseases
Allograft Rejection
Autoimmune Thyroid Disease
Graft-versus-Host Disease
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone Fv17"
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- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-424-F(E) | Recombinant Anti-human GZMB Antibody Fab Fragment | IF, WB, FuncS | Fab |
| MHH-424-F(E) | Recombinant Human Anti-human GZMB Antibody Fab Fragment | RIA, IP, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-424-S(P) | Recombinant Anti-human GZMB Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| MHH-424-S(P) | Recombinant Human Anti-human GZMB Antibody scFv Fragment | WB, Neut, FuncS | scFv |
| FAMAB-0137-YC-S(P) | Human Anti-GZMB Recombinant Antibody (clone Fv17); scFv Fragment | ELISA, FC, WB, IP | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-424 | Recombinant Human Anti-human GZMB Antibody | ELISA, IP, FuncS | IgG |
| MOB-1405MZ | Recombinant Mouse Anti-Human GZMB Antibody (clone HC22) | FC, IHC-Fr, IP | Mouse antibody |
| FAMAB-0137YC | Human Anti-GZMB Recombinant Antibody (clone Fv17) | ELISA, FC, WB, IP | Human IgG |
| ZG-0701J | Rabbit Anti-GZMB Recombinant Antibody (clone 6A1) | ELISA, IHC, IF | Rabbit IgG |
| VS7-0425-WR7 | Mouse Anti-GZMB Recombinant Antibody (clone 2G12G7) | IHC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1551 | Rabbit Anti-GZMB Recombinant Antibody (clone DS1551AB) | IHC-P, ICC, IF, IP | Rabbit IgG |
| MOR-4582 | Rabbit Anti-GZMB Recombinant Antibody (clone TH94DS) | WB, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY117 | AbPlus™ Anti-GZMB Magnetic Beads (Fv17) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY231 | Mouse Anti-NHP GZMB Recombinant Antibody (clone GB11) | WB, IF, FC, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3000 | Anti-GZMB Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC138 | Recombinant Anti-GZMB Eliminating Antibody, pH-Sensitive (Fv17 var.) | Antigen-Sweeping In Vivo. | Human IgG |
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