Recombinant Human Anti-human GZMB Antibody (CAT#: MHH-424)
Recombinant Human Antibody has specificity for an antigen Human GZMB, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-GZMB mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-GZMB mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Normal Tissue
RNA Expression
Figure 1 Bone marrow
(Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3418/10586_B_4_4.jpg
(Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3418/10586_B_4_4.jpg
Figure 2 Lymph node
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3418/10586_A_7_8.jpg
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3418/10586_A_7_8.jpg
Figure 3 RNA cell line category: Cell line enriched (HMC-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100453-GZMB
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100453-GZMB
Specifications
- Immunogen
- Human granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
- Species Reactivity
- Human
- Applications
- Antibody assay: Enzyme-linked Immunosorbent Assay; Immunoprecipitation; Functional Study
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C
Target
- Alternative Names
- GZMB; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1; granzyme B; C11; CTLA-1; fragmentin 2; fragmentin-2; cathepsin G-like 1; human lymphocyte protein; T-cell serine
- Gene ID
- 3002
- UniProt ID
- P10144
Related Resources
Allograft Rejection
Autoimmune Thyroid Disease
Graft-versus-Host Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-424 | Recombinant Anti-human GZMB Antibody | ELISA, WB, IP, FuncS | IgG |
| FAMAB-0137YC | Human Anti-GZMB Recombinant Antibody (clone Fv17) | ELISA, FC, WB, IP | Human IgG |
| ZG-0701J | Rabbit Anti-GZMB Recombinant Antibody (clone 6A1) | ELISA, IHC, IF | Rabbit IgG |
| VS-0224-XY56 | Human Anti-GZMB Recombinant Antibody (VS-0224-XY56) | ELISA | Human IgG1 |
| VS7-0425-WR7 | Mouse Anti-GZMB Recombinant Antibody (clone 2G12G7) | IHC | Mouse IgG2a |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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